LONGITUDINAL STUDY OF OCULAR COMPLICATIONS OF AIDS (LSOCA)

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是了解艾滋病毒感染及其治疗如何影响人们的眼睛和视力。这项研究的目的是：1)监测艾滋病眼部并发症发病率的长期趋势；2)确定HAART诱导的免疫状态变化对艾滋病眼部并发症发生率和病程的影响；3)确定将他们置于眼部并发症高危状态的患者的特征；以及4)评估CMV视网膜炎和其他眼部并发症的治疗对视觉功能、生活质量和生存的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to learn how HIV infections and its treatments affect people's eyes and their sight. The objectives of this study are: 1) to monitor secular trends in the incidence of ocular complications of AIDS; 2) to determine the effect of HAART-induced changes in immune status of the incidence and course of ocular complications of AIDS; 3) to determine the characteristics of patients that place them at high risk for ocular complications; and 4) to evaluate the effects of treatments for CMV retinitis and other ocular complications on visual function, quality of life, and survival.