Advanced Techniques for Cancer Imaging and Detection

癌症成像和检测的先进技术

• 批准号: 7286808
• 负责人: GARY M. GLAZER
• 金额: $ 24.88万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-02-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7286808
• 关键词: Detection; Techniques; cancer imaging

DESCRIPTION (provided by applicant): We are submitting a competing renewal for our longstanding training program in Stanford Radiology under a new name, Advanced Techniques for Cancer Imaging and Detection, to reflect the dramatic changes that this program has undergone since our last application. Our Department is one of the very few that has been able to expand and embrace a multidisciplinary vision necessary to encompass molecular imaging, nanotechnology, and systems biology to augment our strength in anatomic imaging. We have expanded our facilities to offer our trainees experience in cancer imaging and detection techniques that include molecular imaging, nanotechnology, ultrasound, PET/CT, MRI, and computational systems. Our goal is to provide M.D. and Ph.D. trained postdoctoral students with rigorous training towards a career in cancer detection, diagnosis, and therapy based on imaging techniques. Since 1993, we have successfully graduated 21 M.D. and Ph.D. trainees. All trainees were productive during their tenure in the program; many continue academic activity in cancer imaging today. The six current trainees are pursuing research in MR imaging of breast cancer and angiogenesis imaging with nanoparticles; developing MR probes for the diagnosis and treatment of cancer; and cultivating advanced instrumentation for CT and molecular imaging. The need for this program is even greater now than it was in 1993. Since our 2001 application, the field of radiology has dramatically changed and now, more than ever, plays a key role in the diagnosis and treatment of cancer patients. Our program is very committed to fulfilling our mission of training the next leaders in cancer imaging and detection through its unique blend of scientists, clinicians, and educators. Trainees in our program will benefit from the excellent resources within the Department and from those resources available through such disciplines as bioengineering, radiation oncology, electrical engineering, materials science, molecular pharmacology, health policy and research, and cancer biology. Our substantially expanded program will leverage four existing centers of excellence: the In Vivo Cellular and Molecular Imaging Center (ICMIC@Stanford); the Center of Cancer Nanotechnology Excellence (CCNE); the Center for Advanced Magnetic Resonance Technology (CAMRT); and the Computational Modeling of Cancer Biology, which is the Integrative Cancer Biology Program (ICBP) planning grant. Three of these centers have been developed in the last three years. Dr. Gary M. Glazer will continue to direct the program, which will be mentored by twelve established preceptors and seven distinguished program advisors. Trainees are required to participate in courses, seminars, and conferences in clinical cancer, the imaging sciences, biostatistics, and medical ethics. They are also required to complete original, independent research.

描述(由申请者提供)：我们正在为我们在斯坦福放射学的长期培训计划提交一份竞争性续签，新名称为癌症成像和检测高级技术，以反映自我们上次申请以来该计划所经历的巨大变化。我们系是为数不多的能够扩展和接受多学科视野的系之一，这是包括分子成像、纳米技术和系统生物学所必需的，以增强我们在解剖成像方面的实力。我们扩展了我们的设施，为学员提供癌症成像和检测技术方面的经验，包括分子成像、纳米技术、超声波、PET/CT、MRI和计算系统。我们的目标是为经过医学博士和博士学位培训的博士后学生提供严格的培训，以便在基于成像技术的癌症检测、诊断和治疗方面取得成功。自1993年以来，我们已成功毕业21名医学博士和博士研究生。所有受训人员在该项目的任期内都很有成效；许多人今天继续在癌症成像方面进行学术活动。目前的六名学员正在从事乳腺癌的MR成像和纳米颗粒血管生成成像的研究；开发用于癌症诊断和治疗的MR探针；以及培育用于CT和分子成像的先进仪器。 与1993年相比，现在对这一计划的需求更大。自从我们2001年的应用以来，放射学领域发生了巨大的变化，现在比以往任何时候都更在癌症患者的诊断和治疗中发挥着关键作用。我们的项目致力于通过其独特的科学家、临床医生和教育工作者的融合来实现我们的使命，即培养癌症成像和检测领域的下一代领导者。我们计划的学员将受益于系内的优秀资源以及生物工程、放射肿瘤学、电气工程、材料科学、分子药理学、卫生政策和研究以及癌症生物学等学科的资源。 我们大幅扩大的计划将利用四个现有的卓越中心：体内细胞和分子成像中心(ICMIC@Stanford)、癌症纳米技术卓越中心(CCNE)、高级磁共振技术中心(CAMRT)和癌症生物学计算模型(ICBP)计划拨款。其中三个中心是在过去三年中发展起来的。 加里·M·格雷泽博士将继续指导该计划，该计划将由12名知名教官和7名杰出的计划顾问指导。学员必须参加临床癌症、影像科学、生物统计学和医学伦理学方面的课程、研讨会和会议。他们还被要求完成原创的、独立的研究。