Speech Development in Children with Cerebral Palsy

描述（由申请人提供）：脑瘫（CP）是一种非进行性、以神经系统为基础的运动障碍综合征，通常在出生后18个月内被诊断出来（Rosenbaum et al., 2002）。研究表明高达88%的CP患者有构音障碍（Achilles, 1955）。构音障碍的一个重要后果是语音清晰度降低（Yorkston et al., 1999），这反过来又经常导致社会参与和教育/职业追求的干扰。虽然有越来越多的文献研究CP儿童的粗大和精细运动发展（Hanna et al., 2003; Rosenbaum et al., 2002），但还没有研究研究这一人群的语言纵向发展。因此，通过自然语言进行交流的长期预后和结果是不确定的。通过识别对构音障碍儿童的可理解性有贡献的具体变量，对CP儿童的语言发展的研究提供了一个机会来推进一个全面的语言可理解性理论；并说明这些变量是如何随时间变化的，以及这些变化对可理解性的相对影响。凯瑟琳·赫斯塔德博士是威斯康星大学麦迪逊分校的终身助理教授。她的目标是将她目前的研究重点从成人CP扩展到儿童CP的语言发展研究。这项前瞻性纵向研究将收集26名24至48个月大的CP儿童的语音可理解性、频谱和时间声学测量以及语音感知/片段特征的数据，为期四年。威斯曼中心和威斯康辛大学麦迪逊分校非常适合满足职业发展计划的目标，该计划将侧重于Pl的获取：运动发展和儿童运动语言障碍领域的高级内容知识；语音测量技术方面的专业知识，包括声学分析程序和发音困难语音的分段特征；以及纵向研究设计和分析的技术专长，包括临床调查和测量中的一般问题。该项目的主要导师Ray Kent教授在构音障碍和语言科学方面拥有丰富的研究经验和专业知识。他将在语言发展、儿童运动语言障碍和声学分析程序方面提供一对一的指导和指导。

DESCRIPTION (provided by applicant): Cerebral palsy (CP) is a non-progressive, neurologically-based, motor impairment syndrome that is usually diagnosed within the first 18 months of life (Rosenbaum et al., 2002). Research suggests that up to 88% of those with CP have dysarthria (Achilles, 1955). One important consequence of dysarthria is reduced speech intelligibility (Yorkston et al., 1999), which in turn frequently results in interference with social participation and educational / vocational pursuits. Although there is a growing body of literature examining gross and fine motor development in children with CP (Hanna et al., 2003; Rosenbaum et al., 2002), there have been no studies examining the longitudinal development of speech in this population. Thus, long-term prognoses and outcomes for communication via natural speech are uncertain. The study of speech development in children with CP presents an opportunity to advance a comprehensive theory of speech intelligibility by identifying specific variables that contribute to intelligibility in children with dysarthria; and specifying how these variables change over time along with the relative effects of these changes on intelligibility. Katherine Hustad, Ph.D., is a tenure-track assistant professor at the University of Wisconsin - Madison. Her goal is to extend her current research, focused on adults with CP, to the study of speech development in children with CP. The proposed prospective longitudinal study will gather data regarding speech intelligibility, spectral and temporal acoustic measures and perceptual / segmental features of the speech of a cohort of 26 children with CP beginning between the ages of 24 and 48 months over a four year period. The Waisman Center and the University of Wisconsin - Madison are ideally suited to meet the goals of the career development plan, which will focus on the Pl's acquisition of: advanced content knowledge in the domains of motor development and motor speech disorders in children; technical expertise in speech measurement techniques including acoustic analysis procedures and segmental characterization of dysarthric speech; and technical expertise in longitudinal research design and analysis, including general issues in clinical investigation and measurement. The primary mentor for this project, Professor Ray Kent, has extensive research experience and expertise in dysarthria and speech science. He will provide one-on-one instruction and mentorship in the areas of speech development, motor speech disorders in children, and acoustic analysis procedures.