Human parainfluenza and influenza virus hijack the host cell glycosylation machinery to facilitate infection – potential new antiviral drug targets

我们体内的每个细胞都包裹着一层糖，称为糖密码。许多呼吸道病毒通过与这些糖结合来利用这种糖密码引起感染。我的项目是研究呼吸道病毒是否可以改变我们的糖密码，以便更有效地复制和诱导疾病。了解病毒如何利用我们人类细胞中的糖密码，将确定新的干预和治疗策略，以对抗病毒性疾病。

Every cell in our organism is decorated with a coat of sugars, known as sugar code. Many respiratory viruses exploit this sugar code by binding to these sugars to cause infection. My project investigates if respiratory viruses can change our sugar code in order to more efficiently replicate and induce disease. Understanding how viruses can take advantage of the sugar code from our human cells will identify new intervention and treatment strategies to combat viral disease.