TB-AIDS Clinical Training and Research Unit, Russia

说明（由申请人提供）：俄罗斯联邦仍然处于艾滋病毒/艾滋病流行病的前沿，这种流行病正在前苏联各国迅速蔓延。迅速增长的艾滋病毒流行病尚未与结核病流行病合并，创造性和及时的办法可以防止真正的艾滋病毒/艾滋病灾难的发生。导致艾滋病和结核病扩大的社会因素也破坏了俄罗斯的研究基础设施。该申请的目标是确保在俄罗斯第二大城市圣彼得堡建立一个卓越研究培训中心所需的资源，该中心是nih资助的几个项目的所在地。这项申请将汇集一组具有广泛国际和俄罗斯经验以及在艾滋病毒/结核病研究方面的记录的国际研究人员。这些资源将用于建立一个结核病-艾滋病临床培训和研究单位（TACTARU），该单位反过来可以培训新一代医学科学家，以制定针对新出现的结核病和艾滋病流行病的适当对策。TACTARU将派人到耶鲁大学和纽约州立大学接受培训，并将利用五个当地合作机构的专业知识在圣彼得堡制定培训计划。这一国际结核和艾滋病防治合作组织申请的具体目标是：1)通过长期（1-2年）、中期（6 - 12个月）和短期（1-3周）培训计划，提高俄罗斯第二大城市圣彼得堡开展与结核病和艾滋病预防和治疗有关的临床、业务和卫生服务研究的能力。2)通过建立多学科和多机构的TACTARU，改善圣彼得堡所有参与机构的学术培训和研究基础设施。3)建立基础设施，使TACTARU能够成为扩大应对结核病和艾滋病流行的研究能力的国家中心。

DESCRIPTION (provided by applicant): The Russian Federation remains at the forefront of the HIV/AIDS epidemic that is spreading rapidly through the countries of the former Soviet Union. The fast growing HIV epidemic has not yet merged with the Tuberculosis (TB) epidemic and creative and timely approaches could prevent the occurrence of a true HIVTB disaster. The social factors that have resulted in the expansion of AIDS and TB have also damaged the Russian research infrastructure. The goal of this application is to secure the resources necessary to develop a center of excellence in research training in St. Petersburg, Russia's second largest city and the site of several NIH-funded projects. This application will bring together a group of international researchers with extensive international and Russian experience and a track record in HIV/TB research. The resources will be used to develop a TB-AIDS Clinical Training and Research Unit (TACTARU) that can, in turn, train a new generation of medical scientists to develop appropriate responses to the emerging epidemics of TB and AIDS. TACTARU will send individuals to Yale University and the State University of New York for training and will develop training programs in St. Petersburg using the expertise of five local partner institutions. The specific aims of this ICOHRTA application are: 1) To increase the capacity to undertake clinical, operational, and health services research related to TB and AIDS prevention and treatment in St. Petersburg, Russia's second largest city through a mosaic of long-term (1-2 years), intermediate term (6 to 12 months) and short term (1-3 weeks) training plans.2) To improve the academic training and research infrastructure at all participating institutions in St. Petersburg through the establishment of a multidisciplinary and multiinstitutional TACTARU.3) To build an infrastructure that will allow TACTARU to serve as a national center for expanding research capacity in responding to the TB and AIDS epidemics.