NESA Acupuncture Research Collaborative

NESA 针灸研究合作组织

• 批准号: 7596083
• 负责人: Peter Michael Wayne
• 金额: $ 67.83万
• 依托单位: NEW ENGLAND SCHOOL OF ACUPUNCTURE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-25 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7596083
• 关键词: Acupuncture and Oriental Medicine; Acupuncture procedure; Address; Adolescent; Adult; Asians; Award; Boston; Chinese Herbs; Chinese People; Clinical; Clinical Research; Clinical Trials; Collaborations; Communication; Community Medicine; Complementary and alternative medicine; Condition; Dana-Farber Cancer Institute; Data; Development; Diagnosis; Evaluation; Faculty; Foundations; Future; Goals; Grant; Healed; Health; Institutes; Institution; Intervention; Interview; Japanese Population; Joints; Knowledge; Lead; Learning; Malignant neoplasm of ovary; Medical; Medicine; Mentors; Methodological Studies; Methodology; Mind-Body Intervention; Modality; Modeling; Neutropenia; New England; Numbers; Oriental Medicine; Oriental Traditional Medicine; Outcome Measure; Pediatric Hospitals; Phase; Phase I Clinical Trials; Phase II Clinical Trials; Philosophy; Pilot Projects; Play; Procedures; Research; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Research Training; Role; Safety; Schools; Science; Series; Shadowing (Histology); Standards of Weights and Measures; Structure; Students; Testing; Training Programs; Training and Education; Universities; Woman; Women' s Health; Writing; base; chemotherapy; chronic pelvic pain; endometriosis; healing; human subject; improved; instrument; interdisciplinary collaboration; medical schools; novel; pilot trial; programs; research and development; response; skills; sound; tool

As a Developmental Center for Research in Complementary and Alternative Medicine (DCRC), the New England School of Acupuncture (NESA)-Harvard Acupuncture Research Collaborative will bring together leaders from the oriental medicine (OM) and conventional medicine communities to critically evaluate the efficacy and safety of acupuncture, and develop sound methodologies and feasible study designs required for acupuncture research. Our DCRC will strengthen and build upon already ongoing collaborations between NESA, the Harvard Medical School's (HMS) Osher Institute, and two other HMS-affiliated institutions, the Dana Farber Cancer Institute and Children's Hospital Boston. The DCRC will support three developmental/exploratory studies and two infrastructure cores (Administrative and Clinical Trials) that will be synergistically integrated by three themes. The first theme centers around diversifying OM research to evaluate the plurality of approaches employed in clinical practice which will be addressed through the evaluation of both Japanese- and Chinese-style acupuncture. The second theme emphasizes the development and implementation of novel research methods that are required to meet the unique challenges posed in clinical trials of acupuncture and OM. One of our three studies will develop, validate, and test the reliability of an instrument used to derive OM diagnoses in the context of clinical trials. Other methodological issues related to individualization of acupuncture treatments, appropriate controls in acupuncture trials, and the development of outcome measures that reflect the treatment philosophy of OM will also be addressed. The third theme addresses the benefits of acupuncture as an adjunct therapy in the treatment of women's health conditions. Specifically, we will study the application of acupuncture to two conditions for which the current evidence evaluating its efficacy and safety is limited-- chemotherapy-induced neutropenia in women with ovarian cancer, and chronic pelvic pain in adolescent and young women with endometriosis. Integral to our DCRC are a number of academic and administrative mentoring programs through which HMS faculty, staff, and training programs will assist NESA in developing its clinical research infrastructure and capacity to autonomously sustain a productive research program that combines the highest standards of science and the integrity of traditional OM practices. The ultimate goal of our DCRC will be for NESA to play the lead role in the future submission of R01 and R21 proposals that build upon our developmental studies.

作为补充和替代医学（DCRC）研究的发展中心，新英格兰 针灸学院（NESA）-哈佛针灸研究合作将汇集来自 东方医学（OM）和传统医学界，以批判性地评价 针灸，并制定合理的方法和可行的研究设计所需的针灸研究。我们 DCRC将加强和建立在NESA、哈佛医学院 (HMS)Osher研究所，以及另外两个HMS附属机构，达纳法伯癌症研究所和儿童医院， 波士顿医院。DCRC将支持三项开发/探索性研究和两个基础设施核心 （行政和临床试验），将通过三个主题协同整合。第一主题中心 围绕多样化的OM研究，以评估临床实践中采用的多种方法， 通过对日本和中国式针灸的评价来解决。第二个主题强调 开发和实施新的研究方法，以满足所提出的独特挑战， 针灸和OM的临床试验。我们的三项研究之一将开发、验证和测试 用于在临床试验背景下得出OM诊断的工具。与下列方面有关的其他方法学问题： 针灸治疗的个体化，针灸试验中的适当控制，以及结果的发展 反映OM治疗理念的措施也将得到解决。第三个主题涉及以下方面的好处： 针灸作为治疗妇女健康状况的辅助疗法。具体而言，我们将研究 针灸在两种情况下的应用，目前评估其疗效和安全性的证据是 卵巢癌女性患者中有限的化疗诱导的中性粒细胞减少症，青少年和 年轻女性子宫内膜异位症我们的DCRC不可或缺的是一些学术和行政指导 HMS的教职员工和培训计划将通过这些计划协助NESA开展临床研究 基础设施和自主维持生产性研究计划的能力，结合最高标准 科学和传统OM实践的完整性。我们的DCRC的最终目标将是NESA发挥 在未来提交基于我们发展研究的R 01和R21提案中发挥主导作用。