HYPE: Hypertension and preeclampsia after non-steroidal use for post-partum pain relief; a prospective, stratified, randomised placebo-controlled trial

HYPE：使用非类固醇缓解产后疼痛后的高血压和先兆子痫；

• 批准号: nhmrc : 1012398
• 负责人: A/Pr Angela Makris
• 金额: $ 11.64万
• 依托单位: University of Western Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/hype-hypertension-preeclampsia-controlled-trial/109653
• 关键词: HYPE; Hypertension; preeclampsia; after; non

After caesarean delivery of a baby most women will require analgesia. Traditionally anti-inflammatory medications (eg.diclofenac) have been given. Evidence exists that this medicine may increase the mother�s blood pressure. This can result in a longer hospital stay, blood pressure medications and exposure to the risks of high blood pressure (eg.stroke and increased bleeding). This study examines the effect of diclofenac on the mother�s blood pressure, analgesia and investigates the mechanisms behind the increased blood pressure.

剖宫产后，大多数妇女需要止痛。传统的消炎药（如双氯芬酸）已经被给予。有证据表明这种药可能会使母亲的血压升高。这可能导致住院时间延长，需要服用降压药，并面临高血压的风险。中风和出血增加)。本研究探讨双氯芬酸对产妇血压、镇痛的影响，并探讨血压升高背后的机制。