Role of K(G) Channels in Pain and Addiction
Role of K(G) Channels in Pain and Addiction
批准号:
7513857
负责人:
KEVIN D WICKMAN
金额:
$11.1万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-05-01 至 2008-04-30
关键词:
AblationAbsence of pain sensationAcuteAddictive AnalgesicsAddressAdenylate CyclaseAdverse effectsAgonistAnalgesicsBehavioralBehavioral ParadigmBindingCalcium ChannelCellsChronicClassClinicComplementComplexCouplingDevelopmentDynorphinsEffectivenessEnkephalinsEnzymesFamilyFoodGIRK1 subunit, G protein-coupled inwardly-rectifying potassium channelGIRK2 subunit, G protein-coupled inwardly-rectifying potassium channelGIRK3 subunit, G protein-coupled inwardly-rectifying potassium channelGIRK4 subunit, G protein-coupled inwardly-rectifying potassium channelGTP-Binding ProteinsGeneticGoalsHeartIndiumIndividualIntravenousIon ChannelKnock-outKnockout MiceLaboratoriesLeadLinkMeasuresMediatingMolecularMorphineMotor ActivityMusNervous System PhysiologyNervous system structureNeurotransmittersOpiatesOpioidOpioid PeptideOpioid ReceptorPainPain managementPancreasPatternPerformancePharmaceutical PreparationsPhysical DependencePhysiologicalPotassiumPotassium ChannelPsychological reinforcementReagentRelative (related person)ResearchRewardsRoleRole playing therapySelf AdministrationShapesSignal PathwaySignal TransductionSystemTestingTestisVentilatory Depressionaddictionbasedaydesigndesiredrug of abuseendogenous opioidsinsightmembermu opioid receptorsresponsetherapeutic targetvoltage
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会议论文
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依托单位: