Virology Core

病毒学核心实验室的总体目标是加强贝勒学院的艾滋病毒和艾滋病研究 提供全面的最先进的病毒学检测和服务。 病毒学核心实验室还将向CFAR提供其专门的BSL 2/3实验室设施 艾滋病研究人员，并培训这些研究人员正确使用设施。核心由博士领导。 安德鲁·P·赖斯，作为一名从事艾滋病毒研究的分子病毒学家，他有超过16年的经验。爱德华博士 Siwak，副核心总监，一位经验丰富的经理，负责日常监督， 核心核心还包括一名经验丰富的工作人员，他们在由 核心核心的一个主要目标是利用其专业知识，促进合作研究倡议， 其他核心实验室和Baylor-UTHouston CFAR的研究人员。当前主要病毒学核心 服务包括：（1）通过定量微量培养测定HIV-1感染性;（2）基于PCR的 HIV-1 RNA和DNA以及细胞mRNA的测定;（3）p24抗原测定;（4）处理、储存和 运送艾滋病病毒感染者的标本和其他生物样本;以及（5）培训和 使用BSL 2/3设施。最后，病毒学核心有一个计划，每年评估目前的 以及CFAR研究者的未来需求，并根据临床需要为他们提供新的检测和服务， 基础和转化研究项目。

The overall goal of the Virology Core Laboratory is to enhance HIV and AIDS research at Baylor College of Medicine and UTHouston by providing comprehensive state-of-the-art virological assays and services. The Virology Core Laboratory will also make available its specialized BSL2/3 laboratory facilities to CFAR AIDS researchers and train these researchers in the proper usage of the facilities. The Core is headed by Dr. Andrew P. Rice, who has over 16 years' experience as a molecular virologist working on HIV. Dr. Edward Siwak, Associate Core Director, an experienced manager, is responsible for the day-to-day supervision of the Core. The Core also includes an experienced staff with specific expertise in the assays performed by the Core. A major goal of the Core is to exploit its expertise to facilitate collaborative research initiatives with other Core Laboratories and investigators of the Baylor-UTHouston CFAR. Current major Virology Core services include: (1) assays of HIV-1 infectivity by means of quantitative microcultures; (2) PCR-based assays for HIV-1 RNA and DNA and cellular mRNAs; (3) p24 antigen assays; (4) processing, storage and shipment of specimens and other biological samples from patients with HIV infection; and (5) training and usage of BSL2/3 facilities. Finally, the Virology Core has a program in place to evaluate annually the current and future needs of CFAR investigators and provide them with new assays and services as needed for clinical, basic, and translational research projects.