MASS SPECTROMETRY CORE
MASS SPECTROMETRY CORE
批准号:
7246200
负责人:
LASZLO PROKAI
金额:
$11.61万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-08-15 至 2011-05-31
关键词:
CyclotronsCysteineElectrospray IonizationEquipmentFourier TransformIonsLeadershipLiquid ChromatographyLiquid substanceMass Spectrum AnalysisMethodsProteinsProteomicsPurposeReportingResearch PersonnelSamplingServicesSpecialistSteroidsSulfhydryl CompoundsSystemWorkbasegel electrophoresisinstrumentmass spectrometeroxidationreceptortandem mass spectrometry
中文摘要
质谱核心的目的是通过定量分析为项目提供支持
英文摘要
The purpose of the Mass Spectrometry Core is to provide support for the projects by quantitative
determination of steroids by liquid chromatography - tandem mass spectrometry (LC/MS/MS) as its major
activity. Additionally, specialized services will include identification of proteins separated by gel
electrophoresis, identification and quantification of Ca2+-channel/receptor isotypes and their oxidationsensitive
cysteine (Cys) thiols critical to function by methods based on electrospray ionization (ESI) and
LC/MS/MS. These support needs were identified by the project leaders, and the requirements/methods were
discussed in details through interactions with the core director to select the most appropriate ones to be
implemented as core services. Equipments made available on a shared basis are a quadrupole ion-trap
mass spectrometer for steroid analysis and a linear ion-trap - Fourier-transform ion-cyclotron resonance
instrument for proteomics-related work. The systems also incorporate advanced liquid chrom atographs for
sample separations. Core B will provide expert leadership, specialists and technical staff to perform the core
services and provide full reports on the results of quantitative steroid analyses and on protein identification,
quantification to the project leaders and research personnel.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Survey of Age-Associated Carbonylation of Brain Proteins
-
批准号:6863557
-
项目类别:
-
资助金额:$26.67万
-
财政年份:2004
-
负责人:LASZLO PROKAI
-
依托单位:
Survey of Age-Associated Carbonylation of Brain Proteins
-
批准号:7126850
-
项目类别:
-
资助金额:$27.73万
-
财政年份:2004
-
负责人:LASZLO PROKAI
-
依托单位:
Survey of Age-Associated Carbonylation of Brain Proteins
-
批准号:7484105
-
项目类别:
-
资助金额:$26.39万
-
财政年份:2004
-
负责人:LASZLO PROKAI
-
依托单位:
Survey of Age-Associated Carbonylation of Brain Proteins
-
批准号:6950301
-
项目类别:
-
资助金额:$28.4万
-
财政年份:2004
-
负责人:LASZLO PROKAI
-
依托单位:
Survey of Age-Associated Carbonylation of Brain Proteins
-
批准号:7687715
-
项目类别:
-
资助金额:$4.72万
-
财政年份:2004
-
负责人:LASZLO PROKAI
-
依托单位:
Survey of Age-Associated Carbonylation of Brain Proteins
-
批准号:7277804
-
项目类别:
-
资助金额:$26.93万
-
财政年份:2004
-
负责人:LASZLO PROKAI
-
依托单位:
The Role of Quinols in Estrogen Neuroprotection
-
批准号:6831665
-
项目类别:
-
资助金额:$17.45万
-
财政年份:2003
-
负责人:LASZLO PROKAI
-
依托单位:
The Role of Quinols in Estrogen Neuroprotection
-
批准号:7127400
-
项目类别:
-
资助金额:$18.65万
-
财政年份:2003
-
负责人:LASZLO PROKAI
-
依托单位:
The Role of Quinols in Estrogen Neuroprotection
-
批准号:6854720
-
项目类别:
-
资助金额:$4.19万
-
财政年份:2003
-
负责人:LASZLO PROKAI
-
依托单位:
The Role of Quinols in Estrogen Neuroprotection
-
批准号:6697251
-
项目类别:
-
资助金额:$30.2万
-
财政年份:2003
-
负责人:LASZLO PROKAI
-
依托单位:
The Role of Quinols in Estrogen Neuroprotection
-
批准号:7012210
-
项目类别:
-
资助金额:$32.93万
-
财政年份:2003
-
负责人:LASZLO PROKAI
-
依托单位:
The Role of Quinols in Estrogen Neuroprotection
-
批准号:6535003
-
项目类别:
-
资助金额:$31.23万
-
财政年份:2003
-
负责人:LASZLO PROKAI
-
依托单位:
BRAIN TARGETING OF THYROTROPIN RELEASING HORMONE ANALOGS
-
批准号:6528531
-
项目类别:
-
资助金额:$24.75万
-
财政年份:1999
-
负责人:LASZLO PROKAI
-
依托单位:
BRAIN TARGETING OF THYROTROPIN RELEASING HORMONE ANALOGS
-
批准号:6186589
-
项目类别:
-
资助金额:$23.18万
-
财政年份:1999
-
负责人:LASZLO PROKAI
-
依托单位:
BRAIN TARGETING OF THYROTROPIN RELEASING HORMONE ANALOGS
-
批准号:6392617
-
项目类别:
-
资助金额:$23.95万
-
财政年份:1999
-
负责人:LASZLO PROKAI
-
依托单位:
BRAIN TARGETING OF THYROTROPIN RELEASING HORMONE ANALOGS
-
批准号:2908258
-
项目类别:
-
资助金额:$23.55万
-
财政年份:1999
-
负责人:LASZLO PROKAI
-
依托单位:
NEUROPEPTIDE FF ANTAGONISTS FOR TREATING OPIATE ABUSE
-
批准号:2462957
-
项目类别:
-
资助金额:$6.9万
-
财政年份:1998
-
负责人:LASZLO PROKAI
-
依托单位:
NEUROPEPTIDE FF ANTAGONISTS FOR TREATING OPIATE ABUSE
-
批准号:2898064
-
项目类别:
-
资助金额:$7.11万
-
财政年份:1998
-
负责人:LASZLO PROKAI
-
依托单位:
ELECTROSPRAY IONIZATION ATMOSPHERIC PRESSURE CI MS
-
批准号:2040671
-
项目类别:
-
资助金额:$12.59万
-
财政年份:1997
-
负责人:LASZLO PROKAI
-
依托单位:
MASS SPECTROMETRY CORE
-
批准号:8078829
-
项目类别:
-
资助金额:$13.08万
-
财政年份:--
-
负责人:LASZLO PROKAI
-
依托单位:
国内基金
海外基金
基于cysteine代谢在内皮损伤中的作用探讨其在SARSCoV-2感染的致病机理及可能的治疗机制
-
批准号:--
-
项目类别:国际(地区)合作与交流项目
-
资助金额:--
-
批准年份:2020
-
负责人:汪道文
-
依托单位: