Short Course: Integrative and Organ Systems Pharmacology

短期课程：综合和器官系统药理学

• 批准号: 7599785
• 负责人: DAVID B BYLUND
• 金额: $ 17.43万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7599785
• 关键词: Academy; Animal Model; Animals; Antipsychotic Agents; Arrhythmia; Biological; Biological Models; Blood Vessels; Canis familiaris; Cardiac; Cardiovascular Physiology; Cardiovascular system; Caring; Cavia; Cognition; Development; Drug Evaluation; Drug usage; Exercise; Exposure to; Faculty; Goals; Hand; Health; Heart; Heart failure; In Situ; In Vitro; Institutes; Institution; Internships; Ischemia; Laboratories; Laboratory Animals; Lead; Leadership; Learning; Memory; Mental Depression; Methods; Modeling; Molecular; Monkeys; Mus; Nature; Neuropharmacology; Nociception; Numbers; Online Systems; Operative Surgical Procedures; Organ; Oryctolagus cuniculus; Pain; Pharmacology; Physiological Processes; Purpose; Rattus; Regulation; Research; Research Activity; Research Personnel; Rodent; Role; Safety; Schizophrenia; Scientist; Screening procedure; Students; System; Techniques; Tissues; Training; Training Programs; Translational Research; Week; Work; body system; day; design; drug discovery; drug testing; experience; improved; in vivo; instrument; instrumentation; interest; knowledge base; lectures; medical schools; pre-clinical; research study; systems research

DESCRIPTION (provided by applicant): The proposed Short Course in Integrative and Organ Systems Pharmacology is designed to provide graduate students, postdocs, junior faculty and industrial scientists with lectures, demonstrations and hands on experiences with whole animal. This has become an issue of increasing importance as more and more pharmacology training programs have become exclusively cellular and molecular in nature. The course to be offered over two weeks in the summer will focus on cardiovascular and neuropharmacology. Lectures will be provided on the functioning of IACUCs, the humane treatment of animals and regulations appropriate to this, background material on cardiovascular physiology, pharmacology and neuropharmacology. Instrumented animals will be used (dogs, rabbits) for whole animal cardiovascular experiments and various techniques will be used for examining nociception and cognition in rodents. Isolated vascular material and hearts will be used for organ system studies. The drugs used in these experiments will be the same as those used in the instrumented animals. There will also be 1.5 days set aside for elective, hands on, focused experiences selected by the students. An optional third week internship will be available for interested students.

描述（由申请人提供）：拟议的综合和器官系统药理学短期课程旨在为研究生、博士后、初级教师和工业科学家提供讲座、演示和整个动物的实践经验。随着越来越多的药理学培训项目本质上已完全变成细胞和分子，这已成为一个日益重要的问题。夏季为期两周的课程将重点关注心血管和神经药理学。将提供有关 IACUC 功能、动物人道待遇和相应法规、心血管生理学、药理学和神经药理学背景材料的讲座。将使用仪器动物（狗、兔子）进行整个动物心血管实验，并将使用各种技术检查啮齿类动物的伤害感受和认知。分离的血管材料和心脏将用于器官系统研究。这些实验中使用的药物将与仪器动物中使用的药物相同。还将留出 1.5 天的时间用于学生选择的选修、实践、重点体验。有兴趣的学生可以选择参加第三周的实习。