2008 NF Conference

申请者描述(申请人提供)：本申请请求为2008年儿童肿瘤基金会国际核因子会议提供资金支持。会议将于2008年6月6日至10日在佛罗里达州博尼塔斯普林斯的凯悦摄政椰子点度假村举行。自1985年成立以来，这一年度会议已经有了丰硕的历史，它作为核心病界研究人员和临床医生的首要年度聚会发挥了关键作用。会议是来自世界各地的研究人员交流和讨论研究信息的论坛，传统上促进合作、建立共识和推动转化性研究的进展，最终达到临床试验的目的。今年的一项创新是扩大了NF会议，增加了两天的临床数据。要求将更大的临床因素纳入核因子会议是核因子研究从工作台到床边取得进展的一个标志。2005年，美国陆军资助的第二阶段核因子临床试验联盟的出现，在过去两年中促进了核因子临床医生和基础研究人员之间的更多互动，这在核因子会议上得到了证明。2007年，CTF翻译项目史无前例的增长，包括NF临床网络和临床试验奖，促进了临床医生和科学家之间的进一步互动。这是一个在从基础到临床的许多方面都取得了巨大进步的时期，这反映在2008年会议的主题--“从基因到治疗再到并发症”。12个单独的会议将带领该联盟从临床护理数据到核因子的分子机制，以及将模型转化为临床治疗。演讲者包括初级和高级研究人员。这次会议的目标是比较目前在临床研究、生化、细胞和生物系统方面的发现。每一次会议还将包括一位来自核研究之外的领先研究人员的主旨演讲，以开启广泛的讨论。竞争激烈的旅行奖项将带来年轻的研究人员进行口头陈述，两个海报会议将允许研究人员向NF社区展示他们的工作。最后，2008年NF大会的另一项补充是两个小组讨论，这将促使与会者就NF医学界有争议的问题进行讨论。我们采取了两种新的方法，以提高这次会议的知名度和核子研究的状况。首先，为了提高业界对NF的认识，我们将为这次会议寻求大量制药公司的财政赞助。奖励赞助将提供钻石、白金、黄金和白银级别的赞助。其次，联合主席和基金会将共同努力，在《基金会通讯》以及《基金会研究电子新闻》中向10,000多名个人传播关于基金会会议的完整摘要。这些行动将向广大研究界宣传核因子研究的现状、与其他癌症和神经疾病的联系以及需要解决的关键障碍。公共卫生意义：儿童肿瘤基金会国际核因子会议自1985年成立以来，已经有了丰硕的历史，作为核心病界研究人员和临床医生的主要年度聚会，它发挥了关键作用。会议是来自世界各地的研究人员交流和讨论研究信息的论坛，传统上促进合作、建立共识和推动转化性研究的进展，最终达到临床试验的目的。

DESCRIPTION (provided by applicant): This application requests funding support for the 2008 annual meeting of the Children's Tumor Foundation International NF Conference. The Meeting will be held June 6th-10th, 2008, at the Hyatt Regency Coconut Point Resort, Bonita Springs, Florida. This annual meeting has had a fruitful history since its inception in 1985, and it plays a lynchpin role as the premier annual gathering of researchers and clinicians in the NF community. The meeting is a forum for research information exchange and discussion for researchers from around the world, and has traditionally fostered collaboration, consensus building, and advances in translational research culminating in clinical trials. An innovation this year is the expansion of the NF conference with two additional days of clinical data. The demand to include a larger clinical element to the NF Conference is a marker of the progression NF research is making from bench to bedside. The advent of the US Army-funded Phase II NF Clinical Trials Consortium in 2005 has stimulated more interaction between NF clinicians and basic researchers over the past two years and this has been evidenced at the NF Conference. The unprecedented growth of CTF translational programs in 2007, including an NF Clinic Network and Clinical Trial Awards, stimulates further interactions between clinicians and scientists. This is a time of tremendous advances in NF research on many fronts, from basic through clinical, and this is reflected in the theme of the 2008 meeting - "Genes to Therapies to Complications". Twelve individual sessions will take the Consortium from clinical care data to molecular mechanisms of NF and translational models to clinical therapies. Speakers will include both junior and senior researchers. The goal of this meeting is to juxtapose current findings in clinical studies, biochemical, cellular and organismal systems. Each session will also include a keynote address by a leading investigator from outside of NF research to open up broad ranging discussions. Competitive travel awards will bring young investigators for oral presentations, and two poster sessions will allow investigators to present their work to the NF community. Finally, another addition in the 2008 NF conference is the two panel discussions, which will stimulate discussions among the attendees for controversial issues in NF medical community. We have taken two new approaches in order to increase the visibility of this meeting and of the state of NF research. First, to increase industry awareness of NF, we will seek fiscal sponsorship for this meeting from a large number of pharmaceutical companies. Incentive sponsorships will be offered at diamond, platinum, gold and silver levels. Secondly, the cochairs and the Foundation will work together to disseminate a full summary of the NF conference in the NF Newsletter as well in the NF Research E-NewsBlast to over 10,000 individuals. These actions will promote to the research community at large the status of NF research, the link with other cancers and neurological disorders and the key barriers to be addressed. PUBLIC HEALTH RELEVANCE: The Children's Tumor Foundation International NF Conference has had a fruitful history since its inception in 1985, and it plays a lynchpin role as the premier annual gathering of researchers and clinicians in the NF community. The meeting is a forum for research information exchange and discussion for researchers from around the world, and has traditionally fostered collaboration, consensus building, and advances in translational research culminating in clinical trials.