Mechanisms of Leukocyte Integrin Signaling

白细胞整合素信号传导机制

• 批准号: 7531183
• 负责人: Clifford A Lowell
• 金额: $ 31.68万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7531183
• 关键词: 76-kDa SH2 domain-containing leukocyte protein; Acute; Acute Lung Injury; Adhesions; Adhesives; Anti-Inflammatory Agents; Anti-inflammatory; Back; Biochemical; Biochemical Genetics; Blood donor; Cell Adhesion; Cell membrane; Cells; Class; Collaborations; Complex; Data; Defect; Development; Disease; Disruption; Enzymes; Family; Fc Receptor; Fetal Liver; Flow Cytometry; Fluorescence Resonance Energy Transfer; Hematopoietic stem cells; Human; ITAM; Inflammation; Inflammatory; Inflammatory Response; Integrin Signaling Pathway; Integrins; Invaded; Knock-out; LCP2 gene; Laboratories; Leukocytes; Ligands; Link; Lipids; Localized; Lung; Lymphocyte antigen; Macrophage Activation; Mediating; Methods; Microscopy; Mitogen-Activated Protein Kinases; Modeling; Molecular; Mus; Mutant Strains Mice; Mutation; Myeloid Cells; Neutrophil Activation; Pathogenesis; Pathway interactions; Patients; Peptides; Pharmaceutical Preparations; Protein Tyrosine Kinase; Proteins; Reaction; Sensitivity and Specificity; Series; Signal Pathway; Signal Transduction; Signal Transduction Pathway; Signaling Molecule; Site; Staining method; Stains; Structure; T-Cell Receptor; T-Lymphocyte; TYROBP gene; Techniques; Testing; Therapeutic; Tissues; Transfusion; Tyrosine; Vascular Endothelium; Work; adapter protein; base; cellular transduction; diaminopyrimidine; human SYK protein; leukocyte activation; macrophage; mutant; neutrophil; novel; novel strategies; receptor; reconstitution; research study; response; retroviral transduction; retroviral-mediated; src Homology Region 2 Domain; therapeutic target