Traslating Effective Health Behavior Strategies Into Practice for HIV+ Women

描述：这是一项多地点的对照“转化”试验申请，旨在测试一种基于证据的行为干预的传播策略，该策略旨在覆盖感染艾滋病毒的有色人种贫困妇女。在过去的十年里，这个多学科研究小组（迈阿密大学和纽约临床主任网络）对感染艾滋病毒/艾滋病的贫穷有色人种妇女进行了两次行为临床试验（SMART/EST妇女项目）。这些试验表明，在抗逆转录病毒药物依从性、营养、自我效能、应对技能和生活质量方面有显著改善，同时病毒载量、抑郁、焦虑、性风险和药物使用也显著减少。申请人提议测试社区卫生中心的工作人员是否可以接受培训，以便在纽约、新泽西和南佛罗里达这三个美国妇女艾滋病毒感染率最高的地区的社区卫生中心实施SMART/EST妇女项目。从六个月的“试点阶段”开始，完善传播策略，该研究将为社区卫生中心的卫生保健人员提供密集的培训和后续支持，以英语、西班牙语和克里奥尔语提供完整的16次人工干预。是合适的。将评估组织和临床变量，以确定参与的CHCs采用、实施和维持该计划的有效性。

DESCRIPTION: This multisite application for a controlled "translational" trial proposes to test a dissemination strategy for an evidence-based behavioral intervention designed to reach poor women of color living with HIV. Over the past ten years, this multidisciplinary research team (University of Miami and Clinical Directors Network, New York) has conducted two behavioral clinical trials with poor women of color living with HIV/AIDS (the SMART/EST Women's Program) SWP. These trials demonstrated significant improvements in antiretroviral medication adherence, nutrition, self-efficacy, coping skills, and quality of life, accompanied by significant reductions in viral load, depression, anxiety, sexual risk and substance use. The applicants propose to test whether Community Health Center staff can be trained to implement the SMART/EST Women's Program in CHCs in New York, New Jersey and south Florida, three locales with the highest HIV rates for women in the U.S. Beginning with a six month "pilot phase" to refine the dissemination strategy, the study will provide intensive training and follow-up support for CHC health care staff to deliver the entire 16 session manualized intervention in English, Spanish and Creole, as appropriate. Organizational and clinical variables will be assessed to determine the effectiveness of this strategy for the adoption, implementation and maintenance of this program by the participating CHCs.