CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 2005年宣布的CTSA计划在北卡罗来纳大学教堂山分校(UNC-CH)的教职员工和领导层中引起了极大的兴奋。该州刚刚向北卡罗来纳大学做出了每年350万美元的承诺，以支持临床和转化性研究，因此我们感到处于理想的地位，可以创建所需的机构之家。我们征求了300多名教职员工、管理人员和其他利益相关者的意见，这些意见不仅来自北卡罗来纳大学，也来自全州。根据他们的建议，我们建立了翻译与临床科学(TraCS)研究所，并制定了三个简单的目标：准备并增强我们的教职员工、医疗保健提供者和公民的能力，将他们整合到跨学科团队中，他们将积极参与临床和翻译研究的方方面面，设计和执行最高质量的翻译和临床研究项目，并将研究结果转化为更好的健康，迅速传播和实施已证明的进步，以解决州、国家和全球层面的重要健康问题。为了实现这些目标，由整个北卡罗来纳大学系统的资深教员组成的转化研究咨询委员会将与社区合作，确定重要的健康问题并确定优先事项，并将呼吁针对这些优先事项的试点项目提案。包括社区成员在内的TraCS研究科将对校园和全州40多个单位贡献的3000万美元的试点项目提案进行优先排序并提供书面评论。将在社区实施最佳做法，以改善公民的健康。随着社区对TraCS研究所的反馈，这个循环还在继续。创新领军者将帮助组建研究团队，并指导他们找到许多新的核心和咨询服务，旨在支持从板凳到实践的连续过程中的每一步。对TraCS学院的热情延伸到整个北卡罗来纳大学-CH校区，延伸到我们在北卡罗来纳大学系统中的姐妹校园，并延伸到州政府的最高层。新的以社区为基础的机制也将确保与我们州的公民建立充分的伙伴关系。事实上，我们已经成立了四个社区研究单位中的第一个。我们大量的机构承诺，加上本申请所要求的资金，将使TraCS Institute能够实现其作为CTSA网络中的正式合作伙伴的目标。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The announcement in 2005 of the CTSA program generated great excitement among the faculty and leadership of the University of North Carolina at Chapel Hill (UNC-CH). The state had just made an annual commitment of $3.5M to UNC-CH to support clinical and translational research, so we felt ideally positioned to create the required institutional home. We solicited input from over 300 faculty, administrators and other stakeholders drawn not just from UNC-CH but from across the state. Based on their advice, we established the Translational and Clinical Sciences (TraCS) Institute and crafted three simple goals: Prepare and empower our faculty, health care providers, and citizens, assembling them into inter- disciplinary teams that will actively engage in all aspects of clinical and translational research, Design and execute translational and clinical research projects of the very highest quality, and Translate findings for better health, rapidly disseminating and implementing proven advances to solve important health problems at the state, national, and global levels. To meet these goals, the Translational Research Advisory Board, consisting of senior faculty from across the UNC System, will partner with communities to identify and prioritize important health issues and will call for pilot project proposals that address these priorities. The TraCS Study Section, that includes community members, will prioritize and provide written critiques of pilot project proposals for >$30M contributed by over 40 units across campus and the state. Best practices will be implemented in the communities to improve the health of citizens. The cycle continues as communities feedback to the TraCS Institute. Innovation Champions will help form research teams and guide them to the many new cores and consultative services designed to support at every step along the bench-to-practice continuum. Enthusiasm for the TraCS Institute extends across the UNC-CH campus, to our sister campuses in the UNC System, and to the highest levels of state government. Novel community-based mechanisms will also ensure a full partnership with the citizens of our state. Indeed, we have already established the first of four community research units. Our substantial institutional commitments combined with the funds requested in this application will allow the TraCS Institute to fulfill its goals as a full partner in the CTSA network.