CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 2005年宣布的CTSA计划产生了巨大的兴奋之间的教师和领导的北卡罗来纳州大学在查佩尔山（UNC-CH）。该州刚刚向UNC-CH做出了350万美元的年度承诺，以支持临床和转化研究，因此我们感到非常适合创建所需的机构。我们征求了300多名教师，管理人员和其他利益相关者的意见，这些利益相关者不仅来自UNC-CH，而且来自全州。根据他们的建议，我们建立了转化和临床科学（TraCS）研究所，并制定了三个简单的目标：准备和授权我们的教师，医疗保健提供者和公民，将他们组装成跨学科团队，积极参与临床和转化研究的各个方面，设计和执行最高质量的转化和临床研究项目，并将研究结果转化为更好的健康，快速传播和实施已证明的进步，以解决州，国家和全球层面的重要健康问题。为了实现这些目标，转化研究咨询委员会，由来自整个卫生系统的高级教师组成，将与社区合作，以确定和优先考虑重要的健康问题，并将呼吁解决这些优先事项的试点项目提案。TraCS研究部分，包括社区成员，将优先考虑并提供试点项目提案的书面评论，该提案由校园和州内的40多个单位贡献> 3000万美元。将在社区实施最佳做法，以改善公民的健康。随着社区对TraCS研究所的反馈，这一周期继续下去。创新冠军将帮助组建研究团队，并指导他们获得许多新的核心和咨询服务，这些服务旨在支持实验室到实践连续体的每一步沿着。对TraCS研究所的热情延伸到整个UNC-CH校园，到我们的姐妹校园，以及州政府的最高级别。新颖的基于社区的机制还将确保与我们州公民的全面合作伙伴关系。事实上，我们已经建立了四个社区研究单位中的第一个。我们大量的机构承诺与本申请中要求的资金相结合，将使TraCS研究所能够实现其作为CTSA网络全面合作伙伴的目标。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The announcement in 2005 of the CTSA program generated great excitement among the faculty and leadership of the University of North Carolina at Chapel Hill (UNC-CH). The state had just made an annual commitment of $3.5M to UNC-CH to support clinical and translational research, so we felt ideally positioned to create the required institutional home. We solicited input from over 300 faculty, administrators and other stakeholders drawn not just from UNC-CH but from across the state. Based on their advice, we established the Translational and Clinical Sciences (TraCS) Institute and crafted three simple goals: Prepare and empower our faculty, health care providers, and citizens, assembling them into inter- disciplinary teams that will actively engage in all aspects of clinical and translational research, Design and execute translational and clinical research projects of the very highest quality, and Translate findings for better health, rapidly disseminating and implementing proven advances to solve important health problems at the state, national, and global levels. To meet these goals, the Translational Research Advisory Board, consisting of senior faculty from across the UNC System, will partner with communities to identify and prioritize important health issues and will call for pilot project proposals that address these priorities. The TraCS Study Section, that includes community members, will prioritize and provide written critiques of pilot project proposals for >$30M contributed by over 40 units across campus and the state. Best practices will be implemented in the communities to improve the health of citizens. The cycle continues as communities feedback to the TraCS Institute. Innovation Champions will help form research teams and guide them to the many new cores and consultative services designed to support at every step along the bench-to-practice continuum. Enthusiasm for the TraCS Institute extends across the UNC-CH campus, to our sister campuses in the UNC System, and to the highest levels of state government. Novel community-based mechanisms will also ensure a full partnership with the citizens of our state. Indeed, we have already established the first of four community research units. Our substantial institutional commitments combined with the funds requested in this application will allow the TraCS Institute to fulfill its goals as a full partner in the CTSA network.