Administrative Core

行政核心(核心A)将作为一个集中设施，旨在管理所有业务 与此PP相关，并促进合作实验室之间的互动。的主要任务 这一核心构成部分将：a)传达所有构成部分项目的中心科学主题 将指导他们的研究工作；b)管理方案的财务方面，维护财务记录和其他 行政职能；和(C)迅速、适当地分发或协调材料的分发 (化学品、生物制品、配基、放射性配基、受体突变体、抗体、克隆等)根据以下条款制作 核心B和其他项目的赞助。行政核心还将负责 使参与PP的各个实验室之间的操作和通信保持同步 其他相互协作的实验室，不会对项目产生任何影响。这项工作将包括录制 并将生产的材料分发给参与实验室和合作实验室， 同时维护和更新与这一合作努力有关的数据库。更多具体信息 协调工作将包括定期电话会议、与会者年度小组会议和 协作者，以及其他通信，包括维护专门用于 计划项目活动。与内部咨询委员会举行的季度会议，以及 还将在核心A项下组织与外部科学咨询委员会的年度正式会议。 管理核心将维持或增加公共或共享资源， 部件研究项目相关任务的执行情况。一般行政支助 与本计划项目相关，包括财务管理、通信和准备报告 和建议，也将由这一核心基金提供。 核心A建议书还包括所有计划项目组成部分的简要摘要和 参与实验室之间的科学互动概要，包括职权范围， 项目协调和评估。不同协作的协同方面，所有协作都在 这一共同科学和公共卫生利益的专门领域，构成了这一独特的主要力量 多学科的研究成果。

The Administrative Core (Core A) will serve as a centralized facility designed to manage all operations related to this PP and facilitate the interactions between the collaborating laboratories. The major tasks of this Core component will be to: a) communicate the central scientific theme to which all component projects will direct their research efforts; b) manage the fiscal aspects of the PP, maintain financial records and other administrative functions; and (c) promptly and properly distribute or coordinate the distribution of materials (chemicals, biologicals, ligands, radioligands, receptor mutants, antibodies, clones, etc.) produced under the auspices of Core B and the other projects. The Administrative Core will also take responsibility for synchronizing the operations and communications between the individual laboratories involved in the PP and other laboratories which interact collaboratively at no cost to the project. This effort will include recording and distributing materials produced to the participant laboratories and to the collaborating laboratories, together with maintaining and updating the data base related to this collaborative effort. Additional specific coordinating efforts will include regular telephone conferences, the yearly group meeting of participants and collaborators, as well as other communications, including the maintenance of a Web page dedicated to Program Project activities. The quarterly meetings with the Internal Advisory Committee, as well as the yearly formal meeting with the External Scientific Advisory Committee, will also be organized under Core A. The Administrative Core will maintain or increase the common or shared resources that are required for the performance of the inter-related tasks for the component research projects. General administrative support related to this Program Project, including financial management, correspondence, and preparation of reports and proposals, will also be provided by this Core Facility. The Core A proposal also includes a brief summary of all of the Program Project components and an outline of the scientific interactions between the participating laboratories, including lines of authority, program coordination and evaluation. The synergistic aspect of the different collaborations, all working in this specialized area of mutual scientific and public health interest, constitutes a major strength of this unique multidisciplinary research effort.