HUNTINGTON PROTEIN AGGREGATION IN PC12 CELLS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Studies of the dynamics of htt protein in pc 12 cells using N&B fluctuation analysis. Different lengths (25, 97 QP) of the polyglutamine sequence in hht protein will be study. Comparison of the dynimics of aggregation with other cell types (COS7, ST14A).