DEVELOPING TOOLS FOR STRUCTURAL SYSTEMS BIOLOGY

开发结构系统生物学工具

• 批准号: 7723609
• 负责人: KIRBY VANDIVORT
• 金额: $ 12.63万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723609
• 关键词: Address; Attention; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Modeling; Nature; Organism; Range; Regulation; Research; Research Personnel; Resources; Source; Structure; Systems Biology; United States National Institutes of Health; tool; tool development

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The very nature of living systems lies in the harmonious hierarchical assembly, regulation, and function of their biomolecular building blocks. In the past, the Resource has focused its research and modeling tool development mainly on the building blocks, but is now shifting its attention to the assembly level, developing modeling tools for structural systems biology. This shift has required existing tools to become more efficient in order to handle much larger structures, more automated in order to assist the modeler in building and analyzing models, and more comprehensive in order to address the modelers' wider range of tasks.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 生命系统的本质在于其生物分子构件的和谐分层组装、调节和功能。 过去，资源中心的研究和建模工具开发主要集中在构建模块上，但现在正在将注意力转向装配级别，开发 结构系统生物学的建模工具。 这种转变要求现有工具变得更加高效，以便处理更大的结构，更加自动化，以便帮助建模者构建和分析模型，并且更加全面，以便解决建模者更广泛的任务。