Identification of Molecular Signatures in Indigenous and Non-Indigenous Australians with Systemic Lupus Erythematosus to Enable a Precision Medicine Approach.

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Lupus is an incurable illness, strikingly more prevalent and severe in Indigenous Australians. The biological explanation for this has, however, never been explored. Markers measurable in the blood number in the thousands. To discover new drugs, highly complex data analysis methods, known as bioinformatics, are required to analyse the ‘stack’ of these blood markers. This study will be a first in Indigenous Australians with lupus, and will help in patient selection for emerging drugs.