Identification of molecular and cellular pathways predicting susceptibility or resistance to severe dengue fever

鉴定预测严重登革热易感性或抵抗力的分子和细胞途径

• 批准号: nhmrc : 2000466
• 金额: $ 76.15万
• 依托单位国家: 澳大利亚
• 项目类别: International Collaborations
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-molecular-cellular-dengue-fever/1779564
• 关键词: Identification; molecular; cellular; pathways; predicting

This cooperative research project aims to undertake a comprehensive immunological and molecular analysis of individuals with mild versus severe dengue fever recruited at local hospitals in Jakarta, Indonesia. The project will uncover key processes responsible for the development of severe disease. This information will identify specific biomarkers for innovative diagnostic tools for early prediction/detection of cases that will progress to complicated dengue.

该合作研究项目旨在对印度尼西亚雅加达当地医院招募的轻度和重度登革热患者进行全面的免疫学和分子分析。该项目将揭示导致严重疾病发展的关键过程。这一信息将确定用于创新诊断工具的特定生物标志物，用于早期预测/发现将发展为复杂登革热的病例。