REGULATION OF HEPATIC GLUTATHIONE SYNTHESIS

肝脏谷胱甘肽合成的调节

• 批准号: 8076523
• 负责人: Shelly Chi-Loo Lu
• 金额: $ 40.07万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8076523
• 关键词: Anabolism; Antioxidants; Attenuated; Binding; Cell Line; Cell physiology; Cells; Cholestasis; Chronic; Complement; Curcumin; Cytosol; Data; Down-Regulation; Endotoxemia; Ensure; Enzymes; Epigallocatechin Gallate; Exhibits; Fall prevention; Family; Fibrosis; Free Radicals; GCLC gene; GCLM gene; Gene Expression; Genes; Glutamate-Cysteine Ligase; Glutathione; Goals; Growth; Hepatic; Hepatic Stellate Cell; Hepatocyte; Hepatoprotective Agent; Holoenzymes; Hormones; Hour; Human; In Vitro; Inflammatory; Inflammatory Response; Injury; Injury to Liver; Kupffer Cells; Laboratories; Ligation; Lipopolysaccharides; Lithocholic Acid; Liver; Liver diseases; Malnutrition; Mammalian Cell; Messenger RNA; Modeling; Molecular; Mus; Nuclear; Oxidants; Oxidative Stress; Pathogenesis; Pathologic Processes; Patients; Play; Public Health; Publishing; Rattus; Regulation; Reporting; Response Elements; Rodent; Role; Signal Pathway; Staging; Testing; Therapeutic; Therapeutic Effect; Toxin; Transcriptional Regulation; Transgenic Mice; Translating; Treatment Efficacy; Ursodeoxycholic Acid; Work; abstracting; bile duct; cytokine; design; effective therapy; falls; fibrogenesis; gallocatechol; in vivo; insight; macrophage; novel; overexpression; prevent; promoter; protective effect; response; synthetic enzyme; tool; transcription factor