Cryopyrin/NLRP3 Signaling in Inflammation and Innate Immunity
Cryopyrin/NLRP3 Signaling in Inflammation and Innate Immunity
批准号:
8083029
负责人:
Gabriel Nunez
金额:
$38.63万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-06-21 至 2011-05-31
关键词:
AgonistAutoimmune ProcessBiochemicalBiochemical GeneticsCaspase-1Crohn&aposs diseaseCysteine ProteaseDevelopmentDiseaseEtiologyFamilial amyloid nephropathy with urticaria and deafnessFamilial diseaseFamilyFamily memberGeneticGerm-Line MutationGoalsGoutHost DefenseHumanImmunityInfectionInfectious AgentInflammationInflammatoryInflammatory ResponseInheritedInterleukin-18InvadedLaboratoriesLeadLigandsLinkLipoproteinsMediatingMedicalMissense MutationMitochondriaMolecularMutationNatural ImmunityNeonatalParticulate MatterPathogenesisPathway interactionsPlayProductionProteinsRare DiseasesRecurrenceRegulationRoleSepsisSignal TransductionSilicon DioxideSkinStaphylococcus aureusStimulusStreptococcus pyogenesSyndromeSystemTLR2 geneTestingToll-like receptorsToxinUrateWorkbacterial hemolysincytokinein vivoinsightmembermicrobialpathogenpathogenic bacteriaprotein complexreceptorresponse
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly.
RACK1通过促进NLRP3主动构象和炎性组组装来介导NLRP3炎性体激活。
DOI:
10.1016/j.celrep.2020.108405
发表时间:
2020-11-17
期刊:
Cell reports
影响因子:
8.8
作者:
[Duan Y, Zhang L, Angosto-Bazarra D, Pelegrín P, Núñez G, He Y]
通讯作者:
He Y
Cryopyrin/NLRP3 Signaling in Inflammation and Innate Immunity
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批准号:10536627
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项目类别:
-
资助金额:$39.0万
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财政年份:2020
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负责人:Gabriel Nunez
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依托单位:
Bile acids in intestinal homeostasis and allogeneic hematopoietic transplantation
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批准号:10650323
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项目类别:
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资助金额:$32.63万
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财政年份:2020
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负责人:Gabriel Nunez
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依托单位:
Bile acids in intestinal homeostasis and allogeneic hematopoietic transplantation
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批准号:10441581
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项目类别:
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资助金额:$33.47万
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财政年份:2020
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负责人:Gabriel Nunez
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依托单位:
Cryopyrin/NLRP3 Signaling in Inflammation and Innate Immunity
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批准号:9964988
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项目类别:
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资助金额:$39.0万
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财政年份:2020
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负责人:Gabriel Nunez
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依托单位:
Cryopyrin/NLRP3 Signaling in Inflammation and Innate Immunity
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批准号:10308668
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项目类别:
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资助金额:$39.0万
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财政年份:2020
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负责人:Gabriel Nunez
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依托单位:
Bile acids in intestinal homeostasis and allogeneic hematopoietic transplantation
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批准号:10241906
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项目类别:
-
资助金额:$34.3万
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财政年份:2020
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负责人:Gabriel Nunez
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依托单位:
Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis
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批准号:10642900
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项目类别:
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资助金额:$42.37万
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财政年份:2019
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负责人:Gabriel Nunez
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依托单位:
Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis
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批准号:10187558
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项目类别:
-
资助金额:$42.26万
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财政年份:2019
-
负责人:Gabriel Nunez
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依托单位:
Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis
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批准号:10020402
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项目类别:
-
资助金额:$42.26万
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财政年份:2019
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负责人:Gabriel Nunez
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依托单位:
Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis
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批准号:10426166
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项目类别:
-
资助金额:$42.37万
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财政年份:2019
-
负责人:Gabriel Nunez
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依托单位:
Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis
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批准号:9914560
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项目类别:
-
资助金额:$42.26万
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财政年份:2019
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负责人:Gabriel Nunez
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依托单位:
Role of Staphylococcus aureus and Host immunity in Allergic Skin Disease
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批准号:9257980
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项目类别:
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资助金额:$34.1万
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财政年份:2017
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负责人:Gabriel Nunez
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依托单位:
Role of Staphylococcus aureus and Host immunity in Allergic Skin Disease
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批准号:10208712
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项目类别:
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资助金额:$33.29万
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财政年份:2017
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负责人:Gabriel Nunez
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依托单位:
Role of Bacterial Virulence and the Microbiota in Eradication of Enteropathogenic
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批准号:9249038
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项目类别:
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资助金额:$33.82万
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财政年份:2013
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负责人:Gabriel Nunez
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依托单位:
Role of Immunity and the Microbiota in Enteropathogenic E. coli Eradication
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批准号:10197887
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项目类别:
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资助金额:$38.65万
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财政年份:2013
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负责人:Gabriel Nunez
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依托单位:
Bacterial Virulence and the Microbiota in Eradication of Enteropathogenic E. Coli
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批准号:8495692
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项目类别:
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资助金额:$33.82万
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财政年份:2013
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负责人:Gabriel Nunez
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依托单位:
Role of Bacterial Virulence and the Microbiota in Eradication of Enteropathogenic
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批准号:8662258
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项目类别:
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资助金额:$33.82万
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财政年份:2013
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负责人:Gabriel Nunez
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依托单位:
Role of Immunity and the Microbiota in Enteropathogenic E. coli Eradication
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批准号:10424456
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项目类别:
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资助金额:$38.65万
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财政年份:2013
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负责人:Gabriel Nunez
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依托单位:
Role of Mast cells in NLRP3-mediated Skin Inflammation
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批准号:8110049
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项目类别:
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资助金额:$33.59万
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财政年份:2010
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负责人:Gabriel Nunez
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依托单位:
Role of Mast Cells in NLRP3-Mediated Skin Inflammation
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批准号:8506980
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项目类别:
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资助金额:$31.91万
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财政年份:2010
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负责人:Gabriel Nunez
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依托单位: