Properties of Ion Channels that Control Secretion

控制分泌的离子通道的特性

• 批准号: 8038532
• 负责人: JOHN J ENYEART
• 金额: $ 22.88万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-12 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8038532
• 关键词: Addison' s disease; Adipocytes; Adrenal Cortex; Adrenal Glands; Biochemical; Blood Glucose; Brain; Brain Injuries; Calcium; Cattle; Cell membrane; Cell physiology; Cells; Cessation of life; Chronic stress; Circadian Rhythms; Code; Corticotropin; Coupled; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endocrine; Energy-Generating Resources; Event; Gene Expression; Genes; Genetic Transcription; Goals; Hippocampus (Brain); Hour; Hydrocortisone; Hypoglycemia; Ion Channel; Ions; Knowledge; Learning; Liver; Mediating; Membrane; Memory impairment; Messenger RNA; Molecular; Muscle; Pathology; Pathway interactions; Pattern; Peptides; Physiological; Pituitary Gland; Potassium Channel; Production; Property; Proteins; Psychological Stress; Regulation; Research; Role; Signal Pathway; Signal Transduction; Testing; Transcriptional Activation; Zona Fasciculata; abstracting; design; electrical property; energy balance; hypothalamic-pituitary-adrenal axis; mRNA Stability; novel; patch clamp; public health relevance; response; sugar; voltage

项目成果

Ca2+ and K+ channels of normal human adrenal zona fasciculata cells: properties and modulation by ACTH and AngII.

正常人肾上腺束状带细胞的 Ca2 和 K 通道：ACTH 和 AngII 的特性和调节。

• DOI: 10.1085/jgp.201310964
• 发表时间: 2013
• 期刊: The Journal of general physiology
• 作者: Enyeart,JohnJ;Enyeart,JudithA
• 通讯作者: Enyeart,JudithA

Human adrenal glomerulosa cells express K2P and GIRK potassium channels that are inhibited by ANG II and ACTH.

人肾上腺肾小球细胞表达受 ANG II 和 ACTH 抑制的 K2P 和 GIRK 钾通道。

• DOI: 10.1152/ajpcell.00118.2021
• 发表时间: 2021
• 期刊: American journal of physiology. Cell physiology
• 作者: Enyeart,JohnJ;Enyeart,JudithA
• 通讯作者: Enyeart,JudithA

Calcium-dependent inhibition of adrenal TREK-1 channels by angiotensin II and ionomycin.

• DOI: 10.1152/ajpcell.00117.2011
• 发表时间: 2011-05
• 期刊: American journal of physiology. Cell physiology
• 作者: J. J. Enyeart-J.;Haiyan Liu;J. A. Enyeart