Studies on NikD, a Nikkomycin Biosynthetic Enzyme

尼可霉素生物合成酶NikD的研究

• 批准号: 8136841
• 负责人: MARILYN S JORNS
• 金额: $ 30.65万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-02-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8136841
• 关键词: Acids; Acquired Immunodeficiency Syndrome; Aerobic; Affect; Amino Acids; Anabolism; Antibiotics; Antifungal Agents; Binding; Biochemical; Blastomycosis; Bone Marrow; Cancer Patient; Catalysis; Cations; Chemicals; Chitin; Coccidioidomycosis; Complex; Development; Diffusion; Effectiveness; Electron Transport; Electrons; Enzymes; Exhibits; Family; Flavins; Flavoproteins; Funding; Histoplasmosis; Imines; Immunocompromised Host; Incidence; Individual; Infection; Isomerism; Kinetics; Label; Life; Ligand Binding; Ligands; Lysine; Monitor; Monovalent Cations; Mutagenesis; Mutation; Mycoses; N-terminal; Nature; Nucleosides; Organ Transplantation; Oxidases; Oxidation-Reduction; Patients; Peptide Antibiotics; Peptides; Phosphate Buffer; Physiological; Play; Polysaccharides; Population; Potassium Phosphate; Reaction; Research; Role; Scheme; Sodium; Streptogramins; Techniques; Thermodynamics; Transaminases; Transplant Recipients; base; carboxylate; catalyst; chemotherapy; clorobiocin; cofactor; combat; design; functional group; fungus; member; nikkomycin; novel; oxidation; pathogen; pharmacophore; picolinate; potassium ion; prevent; protein protein interaction; research study; small molecule; suicide substrates; tautomer; three dimensional structure