Four-Dimensional Heterogeneity of Fluid Phase Biopsies in Cancer (4DB-Center)

癌症中液相活检的四维异质性（4DB-中心）

• 批准号: 7789838
• 负责人: PETER KUHN
• 金额: $ 200.4万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7789838
• 关键词: Four; Dimensional; Heterogeneity; Fluid; Phase

DESCRIPTION (provided by applicant): The 4DB Center will be directed by the PI, Peter Kuhn (physics), who will be assisted by senior co-investigator Kelly Bethel (oncology). Both are voting members of the Center Advisory Committee (CAC) and will be joined by John Griffin (hematology) and Paul Newton (mathematics/physics). Along with four external scientific advisors as non-voting members and an NCI representative, they will oversee all programmatic and organizational aspects of the Center, its integration with the PS-OC Network and its education and outreach mission. An internal physics oncology interface board will provide additional guidance and institutional support. A key aspect of the CAC's responsibilities will be the development of pilot and trans-network projects to further the 4DB Center research goals as well as to complement the research of the other PS-OC Network centers. The project manager, Enrique Abola, will be responsible for the day-to-day center operations and will report to Drs. Kuhn and Bethel, who are responsible for communication and interaction with the PS-OCs Steering Committee (PSC). The 4DB Center data sharing and communication will be integrated through an enterprise-class software system consisting of a database system, web portal and standalone software programs for data/sample tracking and data annotation/collaboration.

描述（由申请人提供）：4DB 中心将由 PI Peter Kuhn（物理学）领导，并由高级联合研究员 Kelly Bethel（肿瘤学）协助。两人都是中心咨询委员会 (CAC) 的投票成员，约翰·格里芬 (John Griffin)（血液学）和保罗·牛顿（Paul Newton）（数学/物理学）也将加入其中。他们将与四名作为无投票权成员的外部科学顾问和一名 NCI 代表一起监督该中心的所有计划和组织方面、其与 PS-OC 网络的整合及其教育和外展使命。内部物理肿瘤学接口板将提供额外的指导和机构支持。 CAC 职责的一个关键方面是开发试点和跨网络项目，以推进 4DB 中心的研究目标，并补充其他 PS-OC 网络中心的研究。项目经理 Enrique Abola 将负责中心的日常运营，并向 Drs. 报告。 Kuhn 和 Bethel 负责与 PS-OC 指导委员会 (PSC) 的沟通和互动。 4DB中心的数据共享和通信将通过企业级软件系统进行集成，该系统由数据库系统、门户网站和用于数据/样本跟踪和数据注释/协作的独立软件程序组成。