The Transcription Factor SLUG may Drive the Progression of Akt and HER2/neu
转录因子 SLUG 可能驱动 Akt 和 HER2/neu 的进展
基本信息
- 批准号:7847272
- 负责人:
- 金额:$ 3.81万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-09-01 至 2012-08-31
- 项目状态:已结题
- 来源:
- 关键词:African AmericanAntibodiesBiological FactorsBiological MarkersBiological TestingBiotechnologyBreastBreast Cancer CellCancer CenterCancer PatientCancer cell lineCandidate Disease GeneCell Adhesion MoleculesCell LineCell modelCell-Cell AdhesionCellsClinicalClinical TrialsCohort StudiesCultured CellsDataDiseaseDisease OutcomeDisease-Free SurvivalDoctor of MedicineDoctor of PhilosophyDown-RegulationDrug resistanceE-CadherinERBB2 geneEconomic FactorsEpithelialEpithelial CellsEthnic OriginFamilyFreezingFutureGene ProteinsGenesGrowthHispanicsIn VitroInsuranceLaboratoriesLatinaLeadMCF7 cellMalignant NeoplasmsMammary NeoplasmsMammary glandMedicalMentorsMesenchymalMessenger RNAMethodsMicroarray AnalysisMinorityModelingMolecular TargetNamesNeoplasm MetastasisNormal CellOutcomeOutcome StudyPTEN geneParaffinPathogenesisPathway interactionsPatientsPlayPopulationPostdoctoral FellowPredictive ValuePrincipal InvestigatorRaceRecurrenceRegulationResearchResearch DesignResearch PersonnelResistanceResourcesReverse Transcriptase Polymerase Chain ReactionRiskRoche brand of trastuzumabRoleSKBR3SalmonSample SizeSamplingScientistSignal PathwaySignal TransductionSiteSlideSmall Interfering RNASnailsSpecificitySystemTestingTherapeutic InterventionTimeTissuesTransfectionTransgenic MiceTrastuzumabTumor SubtypeTumor TissueUnderrepresented MinorityUnderserved PopulationUniversitiesUp-RegulationWomanabstractingcancer health disparitycancer stem cellcell motilitychemotherapyclinically significantepithelial to mesenchymal transitionerbB-2 Receptorestablished cell lineexperiencehealth care qualityimprovedin vitro Modelin vivoinhibitor/antagonistinterestmalignant breast neoplasmmortalitymouse modelneoplastic cellnoveloverexpressionpreventprognosticreceptorrepositoryresponseself-renewalslugstem cell differentiationtherapy resistanttissue culturetranscription factortumortumor progressionwortmannin
项目摘要
项目成果
期刊论文数量(0)
专著数量(0)
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会议论文数量(0)
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DENNIS J SLAMON其他文献
DENNIS J SLAMON的其他文献
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{{ truncateString('DENNIS J SLAMON', 18)}}的其他基金
HER-2/NEU ALTERATIONS IN BREAST AND OVARIAN CANCER
乳腺癌和卵巢癌中的 HER-2/NEU 改变
- 批准号:
6657487 - 财政年份:2002
- 资助金额:
$ 3.81万 - 项目类别:
PHASE I STUDY IN PATIENTS WITH PERITONEAL CARCINOMATOSIS USING SCH58500
使用 SCH58500 对腹膜癌患者进行的 I 期研究
- 批准号:
6412186 - 财政年份:2000
- 资助金额:
$ 3.81万 - 项目类别:
HER-2/NEU ALTERATIONS IN BREAST AND OVARIAN CANCER
乳腺癌和卵巢癌中的 HER-2/NEU 改变
- 批准号:
6327587 - 财政年份:1999
- 资助金额:
$ 3.81万 - 项目类别:
PHASE I STUDY IN PATIENTS WITH PERITONEAL CARCINOMATOSIS USING SCH58500
使用 SCH58500 对腹膜癌患者进行的 I 期研究
- 批准号:
6451933 - 财政年份:1999
- 资助金额:
$ 3.81万 - 项目类别:
HER-2/NEU ALTERATIONS IN BREAST AND OVARIAN CANCER
乳腺癌和卵巢癌中的 HER-2/NEU 改变
- 批准号:
6203071 - 财政年份:1999
- 资助金额:
$ 3.81万 - 项目类别:
PHASE I STUDY IN PATIENTS WITH PERITONEAL CARCINOMATOSIS USING SCH58500
使用 SCH58500 对腹膜癌患者进行的 I 期研究
- 批准号:
6297814 - 财政年份:1998
- 资助金额:
$ 3.81万 - 项目类别:
PHASE I STUDY IN PATIENTS WITH PERITONEAL CARCINOMATOSIS USING SCH58500
使用 SCH58500 对腹膜癌患者进行的 I 期研究
- 批准号:
6118455 - 财政年份:1998
- 资助金额:
$ 3.81万 - 项目类别:
HER-2/NEU ALTERATIONS IN BREAST AND OVARIAN CANCER
乳腺癌和卵巢癌中的 HER-2/NEU 改变
- 批准号:
6102107 - 财政年份:1998
- 资助金额:
$ 3.81万 - 项目类别:
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