Identification of testis-specific markers of male infertility

男性不育的睾丸特异性标记物的鉴定

• 批准号: nhmrc : 1099002
• 负责人: Dr Peter Stanton
• 金额: $ 42.3万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-testis-specific-male-infertility/662413
• 关键词: Identification; testis; specific; markers; male

Infertility affects 1 in 20 men, and carries major health and financial burdens. Patient management is difficult because there are no tests to monitor testicular function. While sperm number is normally used, their absence in the ejaculate provides no information whether sperm are present in the testis suitable for IVF, or if sperm production could be ‘kick-started’ with hormones. Our goal is to identify new markers of testis function in blood, and then use them to help treat infertile men.

不孕不育影响着二十分之一的男性，并带来重大的健康和经济负担。患者管理很困难，因为没有监测睾丸功能的测试。虽然通常使用精子数量，但精液中精子的缺失并不能提供精子是否存在于适合体外受精的睾丸中，或者是否可以通过激素“启动”精子产生的信息。我们的目标是识别血液中睾丸功能的新标记，然后用它们来帮助治疗不育男性。