Identification, validation and functional analysis of genes and miRNAs involved in recurrent non-small cell lung cancer.

复发性非小细胞肺癌相关基因和 miRNA 的鉴定、验证和功能分析。

• 批准号: nhmrc : 569762
• 负责人: A/Pr Bajee Krishna Sriram
• 金额: $ 6.98万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Postgraduate Scholarships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-validation-functional-lung-cancer/116121
• 关键词: Identification; validation; functional; analysis; genes

Recurrence of lung cancer after treatment affects 20-85% of patients. Current prognostication tools are inaccurate and thus patients receive generic treatments. Our intention is to identify genes involved in recurrence of lung cancer. We foresee that this will translate to earlier identification of at-risk patients enabling individualised less toxic and more successful treatments. We also hope to better understand biology of lung cancer recurrence and discover new targets for treatment.

治疗后肺癌复发影响20-85%的患者。目前的诊断工具是不准确的，因此患者接受一般治疗。我们的目的是确定与肺癌复发有关的基因。我们预计，这将转化为早期识别风险患者，从而实现个性化的毒性更小和更成功的治疗。我们还希望更好地了解肺癌复发的生物学，并发现新的治疗靶点。