Ubiquitin and Cellular Regulation

描述（由申请人提供）：FASEB夏季会议题为“泛素和细胞调节”将于2006年7月22日至27日在佛蒙特州萨克顿河的佛蒙特学院举行。这一会议每两年举行一次，将于2006年、2008年和2010年举行的下三次会议要求为会议提供部分资金。该会议是泛蛋白领域最重要和历史最悠久的会议。 它自1989年以来一直举行，当时研究泛素的研究人员数量增长到临界质量。随着该领域的迅速扩大，会议已经发展到关注最新和最重要的发展。 最后几次会议都获得了超额认购和成功; 73 - 99%的与会者将最后两次会议评为他们参加过的会议的前10%。 许多新到该领域的发言者被包括在内，会谈被缩短，以便可以提出广泛的新研究。 这些会议将在2006年继续举行，预计将再次受到发言者和非发言者的欢迎。 泛素和泛素样蛋白领域继续以惊人的速度增长，因为其他领域的人发现泛素，泛素化机制和泛素结合蛋白在其研究目标中的关键作用。在某些情况下，来自新人的见解已经大大推动了整个领域的发展，这些案例强调了在这种会议上将人们聚集在一起的重要性。 泛素化和人类疾病之间的联系越来越多，据估计，超过5%的哺乳动物基因组致力于泛素化。 会议将突出在邀请演讲者的选择和从摘要中选择的多个演讲方面的突破性进展。 将特别注意让新的、初级的和代表性不足的调查员群体发言。 会议地点在佛蒙特州一所相对偏远的学校，鼓励所有与会者之间的互动，这次会议有一个突出的传统，即密集的海报会议。 根据往年的情况，会议将超额预订;然而，为了促进与会者之间的互动，会议将限制在180名与会者。

DESCRIPTION (provided by applicant): A FASEB Summer Conference entitled 'Ubiquitin and Cellular Regulation' will be held July 22 - 27, 2006, at Vermont Academy, Saxtons River, Vermont. This conference is held biennially and partial funding for the conference is requested for the next three conferences to be convened in 2006, 2008, and 2010. The conference is the leading and longest -standing meeting in the ubiquitin field. It has been held since 1989, when the number of investigators working on ubiquitin grew to a critical mass. The conference has evolved as the field has rapidly expanded to focus on the newest and most significant developments. The last several meetings were oversubscribed and successful; 73 - 99% of participants rated the last two meetings in the top 10% of meetings they had ever attended. Many speakers new to the field were included and the talks were shortened so that a wide range of new research could be presented. These conventions will be continued in 2006, anticipating that they will again be well received by speakers and non-speakers. The field of ubiquitin and ubiquitin-like proteins continues to grow at a striking pace as individuals in other fields find a crucial role for ubiquitin, the ubiquitination machinery, and ubiquitin-binding proteins in their targets of study. In some cases, insights from new individuals have moved the whole field forward dramatically and these cases emphasize the importance of bringing people together at this type of meeting. The growing connections between ubiquitination and human disease are well recognized, and it is estimated that over 5% of mammalian genomes are devoted to ubiquitination. The meeting will highlight breaking advances both in the choice of invited speakers and in multiple talks selected from abstracts. Special attention will be made to give the floor to new, junior, and underrepresented groups of investigators. The location of the conference at a relatively remote school in Vermont encourages interaction among all participants and this conference has an outstanding tradition of intense poster sessions. Based on past years, the conference will be oversubscribed; however, to foster strong interactions between participants the conference is limited to 180 participants.