The Palm Springs Symposia on HIV/AIDS

描述（由申请人提供）：人类免疫缺陷病毒（HIV）是获得性免疫缺陷综合征（AIDS）的病原体。据预测，目前全球约有3 300万人感染了艾滋病毒。尽管我们对艾滋病毒的分子和细胞生物学的理解取得了一些重大进展，但我们对艾滋病发病机制的理解仍然知之甚少。尽管做出了许多努力，但接种疫苗的尝试基本上都失败了。同样，尽管治疗非常有效，但艾滋病毒对药物产生耐药性的机制尚不清楚。十四年来，棕榈泉艾滋病专题讨论会一直是汇集专家和年轻研究人员讨论艾滋病毒和艾滋病研究的主要国家会议之一。该研讨会每年都会提供不断发展的主题，涵盖发病机制、疫苗和药物开发。2009-2011年的主题分别为“HIV和免疫系统：回归基础”、“新的药物靶点和耐药机制”和“导致艾滋病的分子机制”。已经确定了20位受邀演讲者，并接受了2009年会议的邀请。将邀请同样数目的发言者出席以后的会议。继续举行这一亲密会议对于艾滋病毒/艾滋病研究人员社区分享数据、形成合作并在消除作为一种疾病的艾滋病方面取得进展非常重要。

DESCRIPTION (provided by applicant): The human immunodeficiency virus (HIV) is the causative agent for the acquired immune deficiency syndrome (AIDS). It is predicted that globally approximately 33,000,000 individuals are currently infected with HIV. Although a number of significant advances have been made to our understanding of the molecular and cellular biology of HIV, our understanding of the pathogenesis of AIDS remains less well understood. Despite numerous efforts, vaccination attempts have largely failed. Likewise, although therapy is highly effective, the mechanisms by which HIV becomes resistant to drugs are less clearly defined. For fourteen years the Palm Springs Symposium on HIV/AIDS has been one of the leading national meetings bringing together experts and young investigators to discuss research on HIV and on AIDS. The symposium offers evolving topics on an annual basis that cover pathogenesis, vaccines, and drug development. The topics for 2009-2011 are proposed as "HIV and the Immune System: Back to Basics", "Novel Drug Targets and Mechanisms of Resistance", and "Molecular Mechanisms Leading to AIDS", respectively. Twenty invited speakers have been identified and have accepted their invitations for the 2009 meeting. A similar number of speakers will be invited to subsequent meetings. Continuing this intimate meeting is important for the community of HIV/AIDS investigators to share data, to form collaborations, and to make progress on the elimination of AIDS as an illness.