NEPHROLOGY AND HYPERTENSION TRAINING GRANT

肾脏病学和高血压培训补助金

• 批准号: 7929625
• 负责人: CHRISTOPHER S WILCOX
• 金额: $ 7.54万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7929625
• 关键词: Grant; Hypertension; Nephrology; Training

DESCRIPTION (provided by applicant): This is a proposal for a research training program for post-doctoral trainees in Nephrology and Hypertension. The goal is to prepare physicians and scientists to undertake independent investigation in renal and hypertensive disorders and in the basic biology which underlies normal and aberrant kidney function or blood pressure regulation. We emphasize application of cutting edge basic research techniques to health related problems of renal and hypertensive disease that include studies of renal mechanisms of blood pressure and volume homeostasis, receptor regulation, vascular physiology, pharmacology and angiogenesis, intracellular signaling, oxidative stress, effects of gender and pregnancy on vascular function, molecular genetics and interactions between vasoactive factors in the kidney. Candidates will have the MD and/or PhD. Physicians will have completed clinical training in either internal medicine or pediatrics and most will undertake clinical subspecialty training in nephrology. The research training program will be for 2 years, during which patient care activities will be strictly limited. Candidates will be selected by the entire faculty based upon stated career goals in research and academic nephrology, interviews, letters of recommendation, and past performance. Progress of candidates will be assessed by the program director and co-director, individual faculty preceptors, review by the training faculty and review of formal presentations and written progress reports. All training will be carried out at Georgetown University Medical Center, in the laboratories of a cohesive and highly collaborative group of training faculty drawn from the Departments of Medicine, Pediatrics, Pharmacology, Physiology, and Oncology. Five of the seven core faculty are the Pi's of an NIH Program Project Grant. They undertake research supported by core facilities. The training and support faculty are drawn from many departments in the newly formed Cardiovascular Kidney Institute. This provides a cohesive and collaborative research environment in which to provide basic science research training for selected trainees. The aim is to train physicians and post doctoral scientists, for a career in academic nephrology and hypertension.

描述（由申请人提供）： 这是一个肾脏病学和高血压博士后研究培训计划的建议。目标是培养医生和科学家对肾脏和高血压疾病以及作为正常和异常肾功能或血压调节基础的基础生物学进行独立研究。我们强调应用前沿的基础研究技术，以健康相关的肾脏和高血压疾病，包括血压和容量稳态，受体调节，血管生理学，药理学和血管生成，细胞内信号，氧化应激，性别和妊娠对血管功能的影响，分子遗传学和肾脏血管活性因子之间的相互作用的肾脏机制的研究。候选人将拥有MD和/或PhD。医生将完成内科或儿科的临床培训，大多数将接受肾脏病学的临床专科培训。研究培训计划将持续2年，期间将严格限制患者护理活动。候选人将由全体教师根据在研究和学术肾脏学，面试，推荐信和过去的表现所述的职业目标进行选择。候选人的进展将由项目主任和联合主任，个别教师导师评估，由培训教师审查和正式演示文稿和书面进度报告的审查。所有培训将在乔治敦大学医学中心进行，在来自医学，儿科学，药理学，生理学和肿瘤学系的一个具有凝聚力和高度协作性的培训教师小组的实验室中进行。七名核心教师中有五名是NIH计划项目资助的Pi。他们进行由核心设施支持的研究。培训和支持教师来自新成立的心血管肾脏研究所的许多部门。这提供了一个有凝聚力和协作的研究环境，为选定的受训人员提供基础科学研究培训。其目的是培养医生和博士后科学家，从事学术肾脏病学和高血压的职业。