Diabetes Endocrine and Metabolic Diseases

糖尿病内分泌代谢疾病

• 批准号: 7881407
• 负责人: Morris Jay Birnbaum
• 金额: $ 23.38万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1978
• 资助国家: 美国
• 起止时间: 1978-09-15 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7881407
• 关键词: Diabetes Mellitus; Endocrine; Metabolic Diseases

DESCRIPTION (provided by applicant): This is a competitive renewal for our longstanding Training Program in Diabetes, Endocrinology and Metabolic Diseases. During the most recent funding cycle, about 5 postdoctoral fellows were supported each year. A total of 13 trainees working in 10 different labs have been supported. The program is designed to accommodate both Ph.D. scientists as well as physician scientists with M.D. or M.D, Ph.D. degrees, of whom most enter through the Penn Clinical Fellowship Program in Endocrinology, Diabetes and Metabolism. Of the 13 postdoctoral trainees supported by this T32 during the last period, 8 have "graduated" while 5 are currently supported. One of the fellows who gave up the training grant had to do so prematurely due to an unexpected need to leave the country. Of the other seven, three have obtained independent KO8 funding and are presently Instructors in Medicine at the University of Pennsylvania School of Medicine. Two have returned to the clinic with plans to continue research following training in Clinical Endocrinology, one has obtained independent funding through the individual NRSA mechanism, and one has taken a position in private industry. We ask for a continuation of support for five fellows per year, anticipating that most fellows will receive two years of funding, though some one or three. For the next period, we request additional support to allow one of these five fellows to undertake specialized training in Clinical Epidemiology related to diabetes or endocrinology as part of a new program that integrates this training grant with the University of Pennsylvania Masters of Clinical Epidemiology Program. We also request, for the first time, sufficient funds to support three predoctoral students working in the areas of this program during their third through fifth years of graduate school. At present, there are in laboratories directed by our trainers 36 students working towards their Ph.D. theses, the majority focusing on problems relevant to the mission of this T32 and unsupported by training grants. Six (17%) are underrepresented minorities. Our 25 training faculty have primary appointments in nine Medical School Departments and consist of 15 professors, 7 associate professors, and assistant 3 professors. Six members of the training faculty are woman and one is African- American. The significant expansion in the number of mentors relates primarily to the institution of the training track in Clinical Epidemiology. However, two faculty members new to Penn have also been appointed to the training grant. Training grant faculty bring to the program expertise in p-cell development and function, hormone action, physiology, diabetic complications, genetics in humans and model organisms, transcriptional regulation, patient oriented research, epidemiology and biostatistics. This training program continues to provide superb preparation for those scientists committed to careers in research into diabetes, endocrinology and metabolism.

描述（由申请人提供）： 这是我们长期以来在糖尿病，内分泌学和代谢疾病的培训计划的一个有竞争力的更新。在最近的资助周期中，每年约有5名博士后获得资助。在10个不同实验室工作的13名受训人员得到了支助。该计划旨在容纳两个博士学位。科学家以及医学博士的内科科学家或医学博士或哲学博士他们中的大多数是通过宾夕法尼亚大学内分泌学、糖尿病和代谢临床奖学金项目进入的。在上一个时期由该T32支持的13名博士后培训人员中，8人已“毕业”，5人目前正在接受支持。其中一名放弃培训补助金的研究员由于意外需要离开该国而不得不过早放弃。在其他七人中，有三人获得了独立的KO8资助，目前是宾夕法尼亚大学医学院的医学讲师。两人已返回诊所，计划在临床内分泌学培训后继续研究，一人已通过NRSA个人机制获得独立资助，一人已在私营企业任职。我们要求继续每年资助5名研究员，预计大多数研究员将获得两年的资助，但也有一些研究员将获得一年或三年的资助。在下一个时期，我们要求额外的支持，让这五个研究员之一，进行与糖尿病或内分泌学相关的临床流行病学专业培训，作为一个新的计划，将此培训补助金与临床流行病学硕士宾夕法尼亚大学计划的一部分。我们还要求，第一次，足够的资金，以支持三个博士前的学生在研究生院的第三年到第五年期间在该计划的领域工作。目前，在我们的培训师指导下，有36名学生正在攻读博士学位。论文，大部分集中在与T32的使命相关的问题上，没有培训赠款的支持。6个（17%）是代表性不足的少数民族。我们的25名培训教师在9个医学院部门有主要任命，包括15名教授，7名副教授和3名助理教授。培训教员中有六名妇女，一名非裔美国人。导师人数的显著增加主要与临床流行病学培训轨道的建立有关。然而，两名新到宾夕法尼亚大学的教员也被任命为培训补助金。培训补助金教师带来的专业知识，在p细胞的发展和功能，激素的作用，生理学，糖尿病并发症，遗传学在人类和模式生物，转录调控，以病人为导向的研究，流行病学和生物统计学计划。该培训计划继续为那些致力于糖尿病，内分泌学和代谢研究的科学家提供极好的准备。