Developmental Research Program

发展研究计划

• 批准号: 7743213
• 负责人: Timothy Charles Thompson
• 金额: $ 13.95万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7743213
• 关键词: Area; Award; Awareness; Basic Science; Cancer Center; Cancer Patient; Clinical Research; Collaborations; Communities; Complement; Development; Educational Activities; Environment; Evaluation; Extramural Activities; Funding; Goals; Grant; Grant Review; Human; Incidence; Laboratories; Leadership; Letters; Malignant neoplasm of prostate; Modeling; Monitor; Participant; Pilot Projects; Principal Investigator; Process; Program Description; Program Research Project Grants; Prostate; Publications; Quality of life; Reporting; Reproduction spores; Research; Research Personnel; Research Project Grants; Role; Scientist; Selection Criteria; Translating; Translational Research; United States National Institutes of Health; anticancer research; base; career development; flexibility; improved; innovation; interest; mortality; organizational structure; programs; research study; success

The goal ofthe Developmental Research Program ofthe M. D. Anderson Cancer Center Prostate SPORE is to fund promising pilot studies in translational prostate cancer research. As in the initial SPORE, the Developmental Research Program in this new proposal will emphasize the support of translational research studies that can generate clinically testable hypotheses to help us reduce the incidence and mortality of prostate cancer or improve the quality of life of prostate cancer patients. The M. D. Anderson Cancer Center Prostate SPORE Administrative Core will solicit Letters of Intent of no more than two pages for innovative translational research from all institutional investigators, including participants in the SPORE Career Development Program. These applications will be screened by the Program Director and Co-Director as well as the Principal Investigator and Co-Principal Investigator according to objective criteria. Investigators of selected applications will be asked to prepare a five-page proposal modeled after an NIH ROl. As appropriate, the Administrative Core will help investigators submitting proposals to formulate translational specific aims and research plans, as many of these investigators will not have expertise in this area. The process will therefore be a major educational activity and will further stimulate the development of innovative translational research concepts. The proposals will be reviewed and prioritized by the SPORE Leaders (principal Investigators, research project leaders, program directors, and core directors). The projects will be funded for 1 year and will be renewable for an additional year. Developmental Research projects will be evaluated ad hoc and annually by the Program Director/Co-Director, SPORE Leaders, Executive Committee, and the combined Internal/External Advisory Board. Fifteen developmental projects were funded in the initial Prostate SPORE. Investigators receiving Developmental Research grants reported 255 publications related to the research (2001-2006) supported by their grants during 2001-2008. A total of 28 externally reviewed grants were funded. Importantly, two investigators who did not have significant roles in the initial SPORE submission are investigators in major projects or cores in the new Prostate SPORE submission: Drs. Lin (Director, Career Development) and Navone (Leader, Project 4; Special Advisor, Project 3; Collaborator, Core C), highlighting the importance of the Developmental Research Program in identifying projects and investigators with potential value for translational research.

M.D.安德森癌症中心前列腺孢子发展研究计划的目标是 资助有前途的转化前列腺癌研究试点研究。与最初的 SPORE 一样， 这项新提案中的发展研究计划将强调转化研究的支持 可以产生可临床检验的假设的研究，以帮助我们降低疾病的发生率和死亡率 前列腺癌或改善前列腺癌患者的生活质量。 M.D.安德森癌症中心 前列腺 SPORE 管理核心将征求不超过两页的创新意向书 所有机构研究人员（包括 SPORE 职业参与者）的转化研究 发展计划。这些申请也将由项目总监和联合总监筛选 根据客观标准担任首席研究员和联合首席研究员。调查人员 选定的申请者将被要求准备一份仿照 NIH ROl 的五页提案。作为 在适当的情况下，行政核心将帮助调查人员提交提案以制定转化方案 具体目标和研究计划，因为许多研究人员不具备该领域的专业知识。这 因此，这一过程将是一项重大的教育活动，并将进一步刺激创新的发展 转化研究概念。 SPORE 领导人将审查这些提案并确定优先顺序 （主要研究者、研究项目负责人、项目主任和核心主任）。这些项目将是 资助期限为一年，可再续展一年。发展研究项目将 由项目总监/联合总监、SPORE 领导人、执行委员会每年进行临时评估， 以及合并的内部/外部顾问委员会。 最初的前列腺孢子项目资助了 15 个开发项目。研究人员接受发展 研究资助报告了 255 篇与研究相关的出版物（2001-2006 年），这些出版物由其资助 2001年至2008年期间的赠款。共有 28 项经过外部审查的赠款获得资助。重要的是，两名调查员 在最初的 SPORE 提交中没有发挥重要作用的人是重大项目的调查员或 新的前列腺孢子提交中的核心：博士。 Lin（职业发展总监）和 Navone （项目 4 领导者；项目 3 特别顾问；核心 C 合作者），强调了 发展研究计划，以确定具有潜在价值的项目和研究人员 转化研究。