BIOSTATISTICS CORE

9.1.3生物统计学核心。统计数据为设计、实施和分析 基于随机变化数据的实验和研究。因此，生物统计支持是 对Winship癌症研究所的许多研究人员来说至关重要，生物统计学家在以下方面发挥着重要作用： 大多数癌症研究的资助前和资助后阶段。生物统计学共享核心 WCI中的资源是生物统计咨询和相关方法学的共享机构资源 research.它被认为是WCI研究基础设施的重要组成部分。共享 资源作为中心研究者可从中获取统计专业知识用于计划的联络点， 管理和分析他们的研究。生物统计学共享核心包括以下服务：1） 在实验和研究设计方面提供统计专业知识，包括研究建议 开发、样本量确定、随机化程序以及中期审查和最终审查计划 分析; 2）协助撰写手稿的统计部分; 3）审查，结合 临床转化研究委员会（CTRC），所有研究的完整性和统计可靠性 涉及人类受试者; 4）与临床试验办公室互动和合作， 方案，监测和报告临床数据; 5）进行生物统计方法学研究 关于癌症研究中出现的实际问题，如适用于癌症的数学建模 research.支持的研究类型包括临床试验，转化研究，流行病学， 行为科学和基础科学。生物统计学共享资源涵盖所有程序。

9.1.3 Biostatistics Core. Statistics provides a foundation for the design, conduct and analysis of experiments and studies based on data subject to random variation. Consequently, biostatistical support is critical to many investigators at the Winship Cancer Institute and biostatisticians play a fundamental role in both pre- and post-funding award stages of most cancer research studies. The Biostatistics Shared Core Resource in the WCI is a shared institutional resource for biostatistical consulting and related methodological research. It is recognized as a critical component of the research infrastructure at WCI. The Shared Resource serves as a focal point from which Center investigators may draw statistical expertise for planning, management, and analysis of their studies. The Biostatistics Shared Core includes the following services: 1) Provides statistical expertise in the design of experiments and studies, including research proposal development, sample size determination, randomization procedures, and plans for interim reviews and final analysis; 2) Assists with the writing of statistical components of manuscripts; 3) Reviews, in conjunction with the Clinical Translational Research Committee (CTRC), the integrity and statistical soundness of all studies involving human subjects; 4) Interacts and collaborates with the Clinical Trials Office in the development of protocols, and the monitoring and reporting of clinical data; 5) Conducts biostatistical methodology research on practical problems arising in cancer studies, such as mathematical modeling, applicable to cancer research. Types of research supported include clinical trials, translational research, epidemiology, behavioral, and basic science. The Biostatistics Shared Resource spans all Programs.