CLINICAL TRIAL: RTOG 0413 PHASE III STUDY WHOLE BREAST IRRADIATION VS PARTIAL BR

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本试验将评价部分乳房照射（PBI）与全乳房照射（WBI）相比在早期乳腺癌肿块切除术后提供等同的乳房局部肿瘤控制方面的有效性。该研究将比较接受PBI和WBI的妇女的总生存率、无复发生存率和无远处转移生存率。它还将关注与美容、疲劳、治疗相关症状和感知护理便利性相关的生活质量（QOL）问题。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This trial will evaluate the effectiveness of partial breast irradiation (PBI) compared to whole breast irradiation (WBI) in providing equivalent local tumor control in the breast following lumpectomy for early stage breast cancer. The study will compare the overall survival, recurrence-free survival, and distant disease-free survival between women receiving PBI and WBI. It will also look at quality of life (QOL) issues related to cosmesis, fatigue, treatment-related symptoms, and perceived convenience of care.