SC COBRE: ANIMAL PATHOBIOLOGY CORE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 动物病理生物学核心的总体目标是为脂质组学和病理生物学研究人员提供利用动物模型执行其拟议研究项目的能力，并建立新的动物模型来研究疾病的发病机制。动物病理生物学核心将提供1)基因改变的动物，包括转基因和基因敲除小鼠；2)动物模型的必要设施、教师和工作人员专业知识，包括神经退行性变、心血管疾病、癌症和炎症；3)动物病理学专业知识；以及4)所有项目动物的数据库。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall objective of the Animal Pathobiology Core is to provide the SC COBRE in Lipidomics and Pathobiology investigators with the ability to utilize animal models in the execution of their proposed research projects as well as establish new animal models for the investigation of the mechanisms involved in the pathogenesis of disease. The Animal Pathobiology Core will provide 1) gene-altered animals including transgenic and knockout mice; 2) the necessary facilities, faculty and staff expertise for animal models including neurodegeneration, cardiovascular disease, cancer and inflammation; 3) expertise in animal pathology; and 4) a database of all project animals.