SC COBRE: ANIMAL PATHOBIOLOGY CORE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 动物病理生物学核心的总体目标是为脂质组学和病理生物学研究人员提供利用动物模型执行其拟议研究项目的能力，以及建立新的动物模型以研究疾病发病机制。 动物病理学核心将提供1）基因改变的动物，包括转基因和基因敲除小鼠; 2）必要的设施，教师和工作人员的专业知识，包括神经变性，心血管疾病，癌症和炎症的动物模型; 3）动物病理学专业知识;和4）所有项目动物的数据库。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall objective of the Animal Pathobiology Core is to provide the SC COBRE in Lipidomics and Pathobiology investigators with the ability to utilize animal models in the execution of their proposed research projects as well as establish new animal models for the investigation of the mechanisms involved in the pathogenesis of disease. The Animal Pathobiology Core will provide 1) gene-altered animals including transgenic and knockout mice; 2) the necessary facilities, faculty and staff expertise for animal models including neurodegeneration, cardiovascular disease, cancer and inflammation; 3) expertise in animal pathology; and 4) a database of all project animals.