COBRE: PROTEOMICS FACILITY CORE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在后基因组时代，生物医学研究正迅速从大规模的基因表达分析转向这些基因表达的蛋白质的分析。蛋白质识别、定量、翻译后修饰状态和位置占有率、周转率、细胞定位、与疾病状态的相关性以及与其他蛋白质的相互作用已成为现代蛋白质组学研究实验室的实用实验。事实上，蛋白质组学领域已经成为生物医学研究的最新前沿，并无疑将在未来几十年里在我们与人类疾病的斗争中发挥关键作用。Cobre蛋白质组学共享资源代表了我们为中心研究人员提供实现其个人研究目标所需的现代蛋白质组学工具的努力。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In the post-genomic era, biomedical research is rapidly moving from the large-scale analysis of gene expression to the analysis of the proteins these genes express. Protein identification, quantification, post-translational modification status and site occupancy, turnover rate, cellular localization, correlation with disease states, and interactions with other proteins have become practical experiments in modern proteomics research laboratories. Indeed, the field of proteomics has already become the newest frontier of biomedical research, and will undoubtedly play a critical role in our battle against human diseases in the upcoming decades. The COBRE Proteomics Shared Resource represents our effort to provide Center investigators with the modern proteomics tools they need to accomplish their individual research goals.