Southwest Oncology Group U10 Member Site

描述(由申请人提供)： 自1972年以来，韦梅州立大学(WSU)一直是西南肿瘤学小组(SWOG)的活跃机构成员。我们已经招募了超过4500名患者参加临床试验，并通过持续一致地达到和超过患者的应计目标，仍然是贡献最大的机构之一。多年来，教职员工在支持SWOG方面发挥了重要作用，在该组织的行政和科学职能方面发挥了领导作用。威斯康星州立大学的癌症临床研究计划是按照多学科的疾病导向研究方向组织的，其方式类似于SWOG的器官委员会导向。我们教员在SWOG科学委员会中的代表是由在这些研究领域拥有专业知识和承诺的个人组成的。因此，将想法转化为SWOG研究，以及将SWOG研究和那些被NCI指定为高优先级试验的SWOG研究纳入WSU治疗优先事项，都很容易。此外，我们地区独特的人口结构和癌症中心致力于将少数族裔和女性纳入临床试验的承诺，可以在我们招募少数族裔(24%)和女性(52%)参加SWOG临床试验中清楚地体现出来。我们的癌症中心使命声明称，我们是“一个独特的、以城市为基础的研究、病人护理和教育中心，致力于癌症的预防、早期发现、治疗和最终根除”。这一使命与SWOG合作小组的总体使命保持一致，增强了我们在这一研究合作中的持续成功。在这个充满挑战的经济时期，作为U10成员，人们认识到，货币资源不足以完全资助我们所做的具有挑战性的工作。尽管如此，WSU的目标是继续在我们目前参与的水平上提供支持。此外，我们将促进我们的下一代调查人员的教育和成功，以身作则和承诺。劳伦斯·弗莱厄蒂医学博士自1986年以来一直是SWOG成员，并分别于1988年和1990年担任SWOG黑色素瘤委员会联席主席和SWOG黑色素瘤工作组联席主席。自1996年以来，他作为机构PI一直保持着西南理工大学作为SWOG正式成员机构的突出和卓越地位。 首席调查员： Flaherty博士是Karmanos癌症研究所的医学教授和乳腺内科肿瘤科的服务主管。他还担任卡马诺斯癌症研究所的医学主任。在过去的13年里，他一直是WSU/KCI SWOG U10的PI，在这方面有着出色的记录。他是SWOG黑色素瘤委员会的联合主席，也是SWOG乳房委员会的成员。过去，他曾在ASCO教育委员会担任黑色素瘤跟踪负责人。他似乎在积极地为SWOG内部的职位招聘教员。他显然拥有适当的经验和临床试验专业知识，非常适合他的角色。 保护人类主体(简历)：可以接受 没有明显的担忧。 纳入妇女计划(简历)：可以接受 没有明显的担忧。 纳入少数族裔计划(简历)：可以接受 没有明显的担忧。韦恩州立大学的少数民族人数占24%，这是SWOG内部的基准，反映了该中心的人口结构。 列入儿童计划(简历)：可以接受 登记的受试者一般为18岁或以上。 总体建议： 此应用程序的评级为30，并建议提供六年的支持。

DESCRIPTION (provided by applicant): Wayme State University (WSU) has been an active institutional member of the Southwest Oncology Group (SWOG) since 1972. We have enrolled over 4500 patients onto clinical trials and remain one of the highest contributing institutions by meeting and exceeding patient accrual goals in a continuous and consistent manner. Over the years, faculty members have played an important role in support of SWOG, providing leadership in both the administrative and scientific functions of the group. The clinical research program in cancer at WSU is organized along the lines of multidisciplinary disease oriented studies and in a manner which resembles the organ committee orientation of SWOG. Our faculty's representation in scientific SWOG committees is constituted by individuals with expertise and commitment toward these areas of research. Accordingly, the translation of ideas into SWOG studies, and the incorporation of SWOG studies and those bf NCI designated high priority trials into WSU treatment priorities, are easily facilitated. Additionally, the unique demographics of our region and the cancer center commitment to the inclusion of minorities and women into clinical trials can be clearly identified in our recruitment of minorities (24%) and women (52%) into SWOG clinical trials. Our cancer center mission statement states that we are "a unique, urban-based center of research, patient care and education, dedicated to the prevention, early detection, treatment and eventual eradication of cancer". This mission remains consistent with the overall mission of the SWOG cooperative group, enhancing our continued success in this research collaboration. In this challenging economic time and as a U10 member, it is acknowledged that monetary resources are not sufficient to completely fund the challenging work that we do. Despite this, it is the goal of WSU to continue our support at the level we are currently involved. Additionally, we will facilitate the education and success in our next generation of investigators, leading by example and commitment. Lawrence Flaherty, MD has been a SWOG member since 1986 and Co-Chairman of the SWOG Melanoma Committee and Co-Chair of the SWOG Melanoma Working Group since 1988 and 1990, respectively. As the Institutional PI since 1996 he has maintained the prominence and excellence of WSU as a SWOG full member institution. PRINCIPAL INVESTIGATOR: Dr. Flaherty is Professor of Medicine and Service Chief for the Breast Division of Medical Oncology at the Karmanos Cancer Institute. He also serves as the Medical Director of the Karmanos Cancer Institute. He has been the PI for the WSU/KCI SWOG U10 for the past 13 years and has an outstanding track record in this capacity. He is co-chair of the SWOG Melanoma Committee, and sits on the SWOG Breast Committee. In the past he has served on the ASCO Education Committee as a Melanoma Track Leader. He appears to actively recruit faculty to positions within SWOG. He clearly has appropriate experience and clinical trials expertise, and is well suited to his role. PROTECTION OF HUMAN SUBJECTS (Resume): ACCEPTABLE No concerns are evident. INCLUSION OF WOMEN PLAN (Resume): ACCEPTABLE No concerns are evident. INCLUSION OF MINORITIES PLAN (Resume): ACCEPTABLE No concerns are evident. Wayne State accrued 24% minorities which represents the benchmark within SWOG and reflects the demographics of the center. INCLUSION OF CHILDREN PLAN (Resume): ACCEPTABLE Enrolled subjects are generally 18 years of age or older. OVERALL RECOMMENDATION: This application is rated 30 and recommended for six years of support.