Training in the Neurobiology of Movement and Rehabilitation Sciences

描述(由申请人提供)：本提案的目标是为西北大学在西北大学跨部门神经科学(NUIN)计划的框架下创建的运动与康复科学(MRS)新的跨学科计划获得支持。NUIN-MRS计划的使命是培养具有临床和生命/应用科学背景的学生，使他们成为基础、翻译或临床研究方面的康复科学家。这些康复科学家将有能力整合MRS涉及的不同学科的知识，包括神经科学和生理学、工程学和临床科学。培训计划将侧重于运动和康复科学的神经生物学，主要有三个目标：1)了解运动行为和障碍的神经生物学，2)确定和解决MRS对量化方法的需求，以及3)将这些知识应用于开发有效的康复干预措施。西北大学在运动控制、运动残疾和康复以及神经重组的研究方面有着悠久而公认的历史。在这些领域，从以控制运动和运动障碍为重点的基础动物和人体研究，到针对这些运动障碍的新型康复干预措施的开发，在不同层面上进行了广泛的研究。该项目的跨学科性质将允许临床研究人员与基础和应用科学研究人员之间的密切互动，为从实验室到临床的翻译研究培训提供独特的机会。私人投资机构打算在培训方案的第一年总共支持4名博士前学生，在第二到第五年每年支持7名受训人员。该计划将为每位学员提供为期两年的支持。 与公共卫生相关：残疾人数和残疾程度继续增加，这对制定更好和更有效的康复干预措施的必要性产生了明显影响。拟议的NUIN-MRS博士项目将以扎实的基础科学原理为基础，结合量化方法培训康复科学家，使他们能够建立研究计划，开发有效的康复干预措施，更重要的是，将他们转移到临床。

DESCRIPTION (provided by applicant): The goal of this proposal is to attain support for a new interdisciplinary program in Movement and Rehabilitation Sciences (MRS), created at Northwestern University under the umbrella of the Northwestern University Interdepartmental Neuroscience (NUIN) program. The mission of the NUIN-MRS program is to train students with clinical and life/applied science backgrounds to become rehabilitation scientists in basic, translational or clinical research. These rehabilitation scientists will have the ability to integrate knowledge from the various disciplines involved in MRS, including neuroscience and physiology, engineering and clinical sciences. The training program will focus on the neurobiology of movement and rehabilitation sciences, with three main goals: 1) understanding the neurobiology of movement behavior and disorders, 2) identifying and addressing the need for quantitative methods in MRS, and 3) applying this knowledge to the development of effective rehabilitation interventions. Northwestern University has a long and recognized history in the study of motor control, motor disability and recovery, and neural reorganization. Extensive research is performed in these areas at various levels, from basic animal and human studies focused on the control of movement and movement disorders to the development of novel rehabilitation interventions that address these movement disorders. The interdisciplinary nature of the program will allow close interaction between clinical investigators and basic and applied sciences investigators, providing a unique opportunity for training in translational research, going from the laboratory to the clinic. The PIs intend to support a total of 4 predoctoral students in year 1 of the training program and 7 trainees in each of years 2-5. The program will provide support for a total of two years for each trainee. PUBLIC HEALTH RELEVANCE: The number of individuals with disabilities and the extent of the disabilities continue to increase with a clear impact on the need for developing better and more effective rehabilitation interventions. The proposed NUIN-MRS PhD program will train rehabilitation scientists based on solid fundamental science principles combined with quantitative methods to allow them to establish research programs to develop effective rehabilitation interventions and, more importantly, transfer them to the clinic.