Medical Scientist Training Program at University of Texas Southwestern Med Ctr

描述（由申请人提供）：UT西南医学院的MSTP由NIH持续资助了27年，培养医学博士/博士医师科学家，将实验科学原理应用于人类生物学的基本问题，并将其理解转化为疾病的新治疗方法。像其母机构一样，UT西南MSTP已经移动到研究型医学项目的前列。自2004年转向AMCAS申请以来，MSTP从全国高素质的申请人中抽取。MSTP最后一次审查是在2006年。在科学和教育质量方面没有实质性的问题，但是NIH少数民族招募委员会对我们的少数民族招募和保留计划提出了严重的担忧。我们把这些批评牢记在心。通过各种举措，我们在增加多样性方面取得了显著进展，从2006年3%的少数族裔学生增加到2009-2010学年开始时预计12%的少数族裔学生，目前入学的少数族裔学生占22%。MSTP学生通常在开始论文研究之前完成3个研究轮岗和2年的医学院，尽管学生在医学院学习一年后可以选择较少的轮岗和进入研究生院。在研究期间，学生参加高级研究生课程，通过资格考试，并在270名研究生院教职员工之一的实验室工作。MSTP导师资金充足。学生选择导师进行轮岗和论文研究，在研究生院期间效率很高，平均每个学生发表3.6篇论文。大多数毕业生在优秀的机构做临床实习医生。MSTP副院长和联合主任是活跃的医生科学家，他们指导学生通过医学博士/博士的道路。一个由21名成员组成的指导委员会负责招生决定，并帮助制定项目政策。在27年的时间里，该项目已经毕业了147名学生，他们的职业成果支持了NIH对该项目的授权：73%完成了所有培训并在独立岗位上的毕业生正在学术或制药/工业/生物技术领域进行医学研究。

DESCRIPTION (provided by applicant): The MSTP at UT Southwestern Medical School, continually funded by NIH for 27 years, trains MD/PhD physician scientists to bring the principles of experimental science to bear on fundamental problems in human biology and to translate that understanding into new treatments for disease. Like its parent institution, the UT Southwestern MSTP has moved to the front rank of research-based medical programs. Since switching to the AMCAS application in 2004, the MSTP draws from a national base of highly qualified applicants. The MSTP was last reviewed in 2006. There were no substantial questions regarding the quality of the science or the education, but the NIH Committee on Minority Recruitment raised serious concerns about our minority recruitment and retention plan. We have taken these criticisms to heart. Through a variety of initiatives, we have made remarkable strides in increasing diversity, going from 3% underrepresented minority (URM) students in 2006 to a projected 12% URM students at the start of the 2009-2010 academic year, with 22% URM students in the current entering class. MSTP students typically complete 3 research rotations and 2 years of medical school before embarking on dissertation research, although students have the options of fewer rotations and entry Into graduate school after one year of medical school. During the research years, students take advanced graduate courses, pass a qualifying exam, and work in the lab of one of the 270 Graduate School faculty members. MSTP mentors are well-funded. Students select mentors for rotations and dissertation research across the full spectrum of faculty and are productive during graduate school, averaging 3.6 publications per student. Most graduates do clinical residencies at excellent institutions. The MSTP Associate Dean and co-Directors are active physician-scientists who guide students through the MD/PhD path. A 21 member steering committee makes admissions decisions and helps establish program policy. In its 27 years the program has graduated 147 students whose career outcomes support the NIH mandate for the program: 73% of graduates who have completed all training and are in independent positions are doing medical research in an academic or pharmaceutical/industry/biotechnology. PUBLIC HEALTH RELEVANCE: There is an urgent need to train physician scientists who can discover new causes and treatments of diseases. The proposed grant will continue support for the highly successful Medical Scientist Training Program at The University of Texas Southwestern Medical School, which trains MD/PhD students who become future physician scientists.