Administrative Core

该计划的主要目标是推进一种杀微生物剂的阴道内环配方 联合使用可安全地减少艾滋病毒的性传播。整个计划包括3个项目和1个 Science Core由几个关键分包合同组成，这些分包合同将使科学团队能够实现 它的目标。研究人员、实验室和临床研究地点之间的互动对于 这个项目的成功。因此，一个组织良好、定义明确的行政结构是 这是使这一努力取得成功所必需的。行政核心将监督日常工作 管理项目，并确保所有研究地点的沟通和协调。成员们 将与调查人员、药物合作者、NIH 指定的科学咨询小组的代表和成员。核心的目标是 协调该计划的财务和组织方面。核心将负责 维护和审查预算，并将促进与研究有关的旅行。此外，行政人员 将负责确保候选杀菌剂的采购和分销，并监督 两个地点之间的临床样本运输。行政核心人员将安排所有学习 相关的电话会议和年会。核心还将为计划总监提供指导， 项目和核心领导，以实现平稳、机构间复杂的互动，包括协助 分包合同、IRB、临床研究中心和道德委员会在纽约和卢旺达提交的文件， 识别和解决意想不到的问题。

The primary objective of this Program is to advance an intravaginal ring formulation of a microbicide combination to safely reduce the sexual transmission of HIV. The overall Program includes 3 Projects and a Scientific Core and is comprised of several critical subcontracts that will enable the scientific team to achieve its goals. The interactions between the investigators, laboratories and clinical research sites are essential to the success of this Program. Consequently, a well-organized, well-defined administrative structure is necessary to optimize the success of this endeavor. The Administrative Core will oversee the day-to-day management of the Program and ensure communication and coordination of all study sites. The members of the Administrative Core will work closely with the investigators, pharmaceutical collaborators, NIH representatives and members of the designated Scientific Advisory Panel. The aims of the Core are to coordinate the fiscal and organizational aspects of the Program. The Core will be responsible for maintaining and reviewing budgets and will facilitate research related travel. In addition, administrative staff will be responsible for ensuring procurement and distribution of candidate microbicides as well as overseeing the shipment of clinical samples between the sites. The Administrative Core staff will arrange all study related confernce calls and annual meetings. The Core will also provide guidance to the Program Director, Project and Core Leaders for smooth, inter-institutional complex interactions, including assistance with subcontracts, IRB, Clinical Research Center and Ethics Committee submissions in New York and Rwanda, and identifying and resolving unanticipated problems.