Administrative Core

该计划的主要目标是促进杀微生物剂的阴道环制剂 联合使用，以安全地减少艾滋病毒的性传播。整个项目包括三个项目和一个 科学核心，包括几个关键的分包合同，将使科学团队实现 它的目标。研究者、实验室和临床研究中心之间的互动对于以下方面至关重要： 这个计划的成功。因此，一个组织良好、定义明确的行政结构是 为了使这一奋进取得最大的成功。行政核心将监督日常工作， 管理项目，确保所有研究中心的沟通和协调。成员 行政核心将与研究者、药学合作者、NIH 指定的科学咨询小组的代表和成员。核心的目标是 协调该计划的财务和组织方面。核心将负责 维护和审查预算，并将促进与研究有关的旅行。此外，行政人员 将负责确保候选杀微生物剂的采购和分发，并监督 临床样本在研究中心之间的运输。行政核心人员将安排所有研究 相关会议电话和年度会议。核心还将向方案主任提供指导， 项目和核心领导人顺利，机构间复杂的互动，包括协助 分包合同、IRB、临床研究中心和伦理委员会在纽约和卢旺达提交的文件， 识别和解决未预料到的问题。

The primary objective of this Program is to advance an intravaginal ring formulation of a microbicide combination to safely reduce the sexual transmission of HIV. The overall Program includes 3 Projects and a Scientific Core and is comprised of several critical subcontracts that will enable the scientific team to achieve its goals. The interactions between the investigators, laboratories and clinical research sites are essential to the success of this Program. Consequently, a well-organized, well-defined administrative structure is necessary to optimize the success of this endeavor. The Administrative Core will oversee the day-to-day management of the Program and ensure communication and coordination of all study sites. The members of the Administrative Core will work closely with the investigators, pharmaceutical collaborators, NIH representatives and members of the designated Scientific Advisory Panel. The aims of the Core are to coordinate the fiscal and organizational aspects of the Program. The Core will be responsible for maintaining and reviewing budgets and will facilitate research related travel. In addition, administrative staff will be responsible for ensuring procurement and distribution of candidate microbicides as well as overseeing the shipment of clinical samples between the sites. The Administrative Core staff will arrange all study related confernce calls and annual meetings. The Core will also provide guidance to the Program Director, Project and Core Leaders for smooth, inter-institutional complex interactions, including assistance with subcontracts, IRB, Clinical Research Center and Ethics Committee submissions in New York and Rwanda, and identifying and resolving unanticipated problems.