Clinical Epidemiology and Health Services Research

临床流行病学和卫生服务研究

• 批准号: 8080967
• 负责人: MARI M KITAHATA
• 金额: $ 15.87万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8080967
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adherence; American; Anti-Retroviral Agents; Applications Grants; Behavioral; Biometry; Cardiovascular Diseases; Clinical; Clinical Data; Clinical Research; Collaborations; Collection; Data; Data Sources; Development; Disease; Disease Management; Effectiveness; Electronics; Epidemiologist; Fostering; Funding; Goals; HIV; HIV Infections; Health Services; Health Services Research; Healthcare; Hepatitis C virus; Human Resources; Infection; Information Systems; International; Link; Lipodystrophy; Measures; Mental Depression; Mental Health; Metabolic; Multi-Drug Resistance; Outcome; Outcomes Research; Patients; Persons; Population; Populations at Risk; Postdoctoral Fellow; Registries; Research; Research Design; Research Methodology; Research Personnel; Research Support; Resources; Retrovirology; Scientist; Site; Source; Specimen; Students; Study Subject; Substance abuse problem; System; Technology; Training; Translational Research; Treatment Efficacy; Treatment outcome; Universities; Washington; antiretroviral therapy; base; clinical epidemiology; clinical practice; cohort; drug resistant virus; experience; interdisciplinary approach; meetings; patient registry; repository; research study; translational study

The goals of the UW CFAR Clinical Epidemiology and Health Services Research Core (CE&HSR) (formally Health Services Research Core) are to support clinical and translational HIV/AIDS research by UW CFARaffiliated investigators by providing longitudinal HIV/AIDS patient information and expertise in clinical epidemiology and health services research methods; and to foster interdisciplinary approaches to questions concerning HIV/AIDS by facilitating collaborations between clinician researchers, epidemiologists, health services researchers, biostatisticians, behavioral, and basic scientists. A main goal of the Core is to promote clinical HIV/AIDS research examining the long-term outcomes of HIV-infected patients in routine clinical practice, including the effects of antiretroviral therapy, co-morbid conditions, and complications of treatment. Additional goals of the Core are to support the conduct of interventional studies and to facilitate translational research by supplying clinical patient data linked to specimens collected on the HIV-infected population. At the start of its fifth year of the current funding cycle, the CE&HSR Core has accomplished and exceeded the goals set forth in our last application. The UWHIS has been expanded to capture new data types to support research on key HIV subpopulations. The Core maintains a registry of HIV-infected patients who are willing to participate in research studies and supports researchers preparing grant applications by identifying registry patients who meet proposed study criteria, providing lists of potential study subjects for recruitment, and addressing questions concerning clinical outcomes for persons with HIV/AIDS. The CE&HSR Core provides support to the UW HIV Specimen Repository and collaborates with the Clinical Research, Developmental, Biometrics, and Clinical Retrovirology cores to support new investigator awardees, clinical outcomes research, and translational research. Core personnel have been active in national and international cohort collaborations such as the CFAR Network of Integrated Clinical Systems (CNICS) and the North American region of the (IEDEA) project, the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). Finally, Core resources are being used to implement technology to facilitate the collection of new patient-based measures on adherence, lipodystrophy, depression, HRQL, and substance abuse.

UW CFAR临床流行病学和卫生服务研究核心（CE&HSR）的目标（正式 卫生服务研究核心）是支持临床和转化艾滋病毒/艾滋病研究的UW CFR附属 研究人员通过提供纵向艾滋病毒/艾滋病患者的信息和专业知识， 流行病学和卫生服务的研究方法;并促进跨学科的方法来解决问题 通过促进临床研究人员、流行病学家、卫生保健工作者、 服务研究人员、生物统计学家、行为和基础科学家。核心的一个主要目标是促进 艾滋病毒/艾滋病临床研究，检查艾滋病毒感染者在常规临床 这一做法，包括抗逆转录病毒治疗的影响，共病条件，和治疗的并发症。 核心的其他目标是支持进行干预性研究，并促进转化 通过提供与从艾滋病毒感染人群中收集的标本相关的临床患者数据，开展研究。 在当前资金周期的第五年开始时，CE&HSR核心已经完成， 超过了我们上次申请的目标UWHIS已扩展到捕获新数据 支持对艾滋病毒主要亚群的研究。该中心对艾滋病毒感染者进行登记 谁愿意参与研究，并支持研究人员准备拨款申请， 确定符合拟定研究标准的登记研究患者，提供潜在研究受试者列表， 招募和处理有关艾滋病毒/艾滋病患者临床结果的问题。的 CE&HSR核心为UW HIV标本库提供支持，并与临床 支持新研究者的研究、开发、生物统计学和临床逆转录病毒学核心 获奖者，临床结果研究和转化研究。核心人员一直活跃在 国家和国际队列合作，如CFAR综合临床系统网络 （CNICS）和北美区域（IEDEA）项目，北美艾滋病队列 研究与设计合作（NA-ACCORD）。最后，核心资源正用于实施 技术，以促进收集新的基于患者的措施，坚持，脂肪代谢障碍， 抑郁症HRQL和药物滥用