Cell Free System for Identification of MHC Class II Immunodominant Epitopes

用于鉴定 MHC II 类免疫显性表位的无细胞系统

• 批准号: 8300254
• 负责人: Scheherazade Sadegh-Nasseri
• 金额: $ 32.8万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8300254
• 关键词: Address; Algorithms; Alleles; Amino Acid Sequence; Antigen Presentation; Antigen Presentation Pathway; Antigens; Area; Autoimmune Diseases; Autoimmune Process; B-Lymphocytes; Binding; Biological Assay; CD4 Positive T Lymphocytes; CD8B1 gene; California; Cathepsins; Cell-Free System; Cells; Clinical; Clinical Trials; Collaborations; Complex Mixtures; Computers; Data; Dendritic Cells; Development; Epitopes; Exposure to; Future; Generations; Goals; HLA-DR Antigens; HLA-DR1 Antigen; HLA-DR2 Antigen; Histocompatibility Antigens Class II; Human; Human Volunteers; Immune response; Immune system; Immunodominant Epitopes; Immunologics; Individual; Infection; Infectious Agent; Influenza; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Knowledge; Life; MHC Class II Genes; Malaria; Mass Spectrum Analysis; Memory; Memory B-Lymphocyte; Methods; Mus; Parents; Peptide Mapping; Peptides; Phase; Population; Production; Proteins; Research; Staging; System; T cell response; T memory cell; T-Cell Activation; T-Cell Proliferation; T-Lymphocyte; T-Lymphocyte Epitopes; TCF Transcription Factor; TNFRSF10A gene; Technology; Testing; Therapeutic Intervention; Transgenic Mice; Vaccination; Vaccines; Virus; antigen processing; base; caucasian American; cytokine; design; fighting; human subject; immunogenic; immunogenicity; in vivo; influenza virus vaccine; influenzavirus; memory CD4 T lymphocyte; new technology; novel; novel therapeutics; pathogen; response; seasonal influenza; swine flu; synthetic peptide; tool; vaccine development