Long-term Oxygen Treatment Trial

长期氧气治疗试验

• 批准号: 8340978
• 负责人: James A Tonascia
• 金额: $ 103.33万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-10-31 至 2015-10-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340978
• 关键词: Chronic Obstructive Airway Disease; Clinical; Data Coordinating Center; Hypoxemia; Outcome Measure; Oxygen; Oxygen Therapy Care; Patients; Quality of life; Randomized Controlled Clinical Trials; mortality; treatment trial

The Long-term Oxygen Treatment Trial (LOTT) is a randomized controlled clinical trial to assess the efficacy of around-the-clock, supplemental oxygen therapy in subjects with chronic obstructive pulmonary disease (COPD) and moderately severe hypoxemia. Mortality and quality of life are the major outcome measures. LOTT involves a Data Coordinating Center and 14 Regional Clinical Centers.

长期氧疗试验(LOTT)是一项随机对照临床试验，旨在评估24小时补充氧疗对慢性阻塞性肺疾病(COPD)和中重度低氧血症患者的疗效。死亡率和生活质量是衡量结果的主要指标。LOTT涉及一个数据协调中心和14个地区临床中心。