CLINICAL TRIAL: A PHASE II STUDY OF REPEAT INTRANODAL INJECTIONS OF ADENOVIRUS-C

临床试验：重复结内注射腺病毒-C 的 II 期研究

• 批准号: 8166870
• 负责人: JANUARIO E CASTRO
• 金额: $ 1.33万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166870
• 关键词: Adenoviruses; Biological; Clinical; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Injection of therapeutic agent; Institution; Monitor; Patients; Pharmacodynamics; Phase; Research; Research Personnel; Resources; Safety; Source; United States National Institutes of Health; lymph nodes; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Primary Objectives 1)Determine and monitor clinical and biological responses in patients treated with repeat intranodal injections of Ad-ISF35. Secondary Objectives 1)Determine the safety of repeat administration of Ad-ISF35 injected directly into lymph nodes of patients with CLL / SLL. 2)Determine pharmacodynamic (PD) parameters in patients treated with repeat intranodal injections of Ad-ISF35.

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