AUDITORY & VISUAL INTEGRATION IN SCHIZOPHRENIA EXAMINED USING MEG, EEG & FMRI

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在项目2的第二年，我们继续从我们的听觉/视觉多感觉整合范式中收集数据，以便通过测试精神分裂症患者(SP)相对于健康对照组(HC)的简单多感觉整合反应的影响，更好地了解单一感觉缺陷如何影响更高的认知功能。尽管由于安装了新的Elekta Neuromag Meg机器，数据收集在第一年就被推迟了，但我们在赶上数据收集方面取得了重大进展。表1概述了项目2的数据收集现状。MEG机器于7月底安装完毕，项目2的数据收集工作于2009年10月初开始。这导致功能磁共振成像和脑磁图/脑电数据收集之间的数量不平衡。我们能够收集到6名参与者的BioSemi EEG数据，他们没有被招募回来参加MEG/EEG课程。 总计80 70 51 51 23 我有一份手稿正在修订中，报告了来自实验性AV整合范例的规范数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In year 2 of Project 2 we have continued to collect data from our auditory/visual multisensory integration paradigm in order to better understand how unisensory deficits may impact higher cognitive functioning by testing the effects on simple multisensory integration responses in patients with schizophrenia (SP) relative to healthy controls (HC). Although data collection was delayed in the first year due to the installation of the new Elekta Neuromag MEG machine, we have made significant progress in catching up with data collection. The current status of data collection for Project 2 is outlined in Table 1. The MEG machine was installed at the end of July and data collection began for Project 2 at the beginning of Oct. 2009. This led to an imbalance in the numbers between the fMRI and MEG/EEG data collection. We were able to collect BioSemi EEG data on 6 of the participants who were not recruited back for the MEG/EEG session. Total 80 70 51 51 23 I have a manuscript under revision reporting normative data from the experimental AV integration paradigm.