DOPAMINERGIC VARIANTS INVOLVED IN SMOKING BEHAVIOR: A PERFUSION FMRI STUDY

与吸烟行为相关的多巴胺能变异：灌注 FMRI 研究

• 批准号: 8169078
• 负责人: TERESA R FRANKLIN
• 金额: $ 0.87万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169078
• 关键词: Behavioral; Behavioral Assay; Brain; Candidate Disease Gene; Computer Retrieval of Information on Scientific Projects Database; Exposure to; Functional Magnetic Resonance Imaging; Funding; Genetic Polymorphism; Grant; Institution; Perfusion; Research; Research Personnel; Resources; Satiation; Smoker; Smoking; Smoking Behavior; Source; United States National Institutes of Health; Variant; Withdrawal; addiction

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This R21 project utilizes ASL perfusion fMRI, smoking behavioral assays and a functional candidate gene association approach of dopaminergic addictions-targeted polymorphisms to examine the brain and behavioral activity of smokers under conditions of satiety and withdrawal during exposure to smoking reminders.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这个R21项目利用ASL灌注fMRI，吸烟行为测定和功能候选人 多巴胺能成瘾靶向多态性的基因关联方法， 吸烟者在饱腹感和戒断状态下的大脑和行为活动 暴露在吸烟提醒物中。