Long-term Oxygen Treatment Trial

长期氧气治疗试验

• 批准号: 8481457
• 负责人: Gerard J Criner
• 金额: $ 122.26万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-10-31 至 2014-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8481457
• 关键词: Chronic Obstructive Airway Disease; Clinical; Data Coordinating Center; Hypoxemia; Outcome Measure; Oxygen; Oxygen Therapy Care; Patients; Quality of life; Randomized Controlled Clinical Trials; mortality; treatment trial

The Long-term Oxygen Treatment Trial (LOTT) is a randomized controlled clinical trial to assess the efficacy of around-the-clock, supplemental oxygen therapy in subjects with chronic obstructive pulmonary disease (COPD) and moderately severe hypoxemia. Mortality and quality of life are the major outcome measures. LOTT involves a Data Coordinating Center and 14 Regional Clinical Centers.

长期氧疗试验 (LOTT) 是一项随机对照临床试验，旨在评估全天候补充氧疗对患有慢性阻塞性肺病 (COPD) 和中度严重低氧血症的受试者的疗效。死亡率和生活质量是主要的结果指标。 LOTT 涉及一个数据协调中心和 14 个区域临床中心。