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Ox40 mediated co-stimulation overcoming tumor-induced CD8 T cell peripheral toler

Ox40 mediated co-stimulation overcoming tumor-induced CD8 T cell peripheral toler
Ox40介导的共刺激克服肿瘤诱导的CD8 T细胞外周耐受
批准号：
8269372
负责人：
William L Redmond
金额：
$24.15万
依托单位：
PROVIDENCE PORTLAND MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-07-01 至 2014-06-30
来源：
https://reporter.nih.gov/project-details/8269372
关键词：
AgonistAntibodiesAntibody TherapyCD4 Positive T LymphocytesCD8B1 geneCancer PatientCellsClinical TrialsDataDevelopmentFamilyFamily memberFutureGenerationsImmune responseInterleukin 2 Receptor GammaInterleukin-2Interleukin-4LaboratoriesLeadLigationMalignant NeoplasmsMalignant neoplasm of prostateMediatingMolecularMolecular ProfilingMusPeptidesPeripheralPhase I Clinical TrialsProstatic NeoplasmsRegulationSignal PathwaySignal TransductionT cell anergyT cell responseT-LymphocyteTestingTumor ImmunityTumor Necrosis Factor Receptorabstractinganergybasecytokinecytokine therapyfunctional restorationin vivoinsightlymph nodesmembernovel therapeuticsperipheral tolerancepre-clinical researchpromoterreceptor expressionresearch studytumortumor necrosis factor receptor superfamily member 4

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Ox40 mediated co-stimulation overcoming tumor-induced CD8 T cell peripheral toler
Ox40 mediated co-stimulation overcoming tumor-induced CD8 T cell peripheral toler
Ox40 mediated co-stimulation overcoming tumor-induced CD8 T cell peripheral toler
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