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THE INVOLVEMENT OF TMC PROTEINS IN CELLULAR STRESS RESPONSES

THE INVOLVEMENT OF TMC PROTEINS IN CELLULAR STRESS RESPONSES
TMC 蛋白参与细胞应激反应
批准号:
8360706
负责人:
Alexander James Stokes
金额:
$6.89万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-06-01 至 2012-05-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是利用这些资源的众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The central hypothesis of this project is that the TPCN1 calcium release channel is in part responsible in regulating the key transient increases in intracellular calcium concentration needed for the correct progression of cytokinesis. In addition, it is hypothesized that this regulation is via direct involvement of the regulatory kinases responsible for myosin light chain 2-phosphorylation, activation, and the subsequent cleavage furrow formation necessary for completion of cytokinesis.
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TRPA1 Physiology in Diabetes, Metabolic Syndrome, and Metabolism
  • 批准号:
    9211067
  • 项目类别:
  • 资助金额:
    $23.1万
  • 财政年份:
    2017
  • 负责人:
    Alexander James Stokes
  • 依托单位:
ION CHANNEL DETERMINANTS OF MAST CELL ACTION IN THE HEART
  • 批准号:
    8360591
  • 项目类别:
  • 资助金额:
    $27.51万
  • 财政年份:
    2011
  • 负责人:
    Alexander James Stokes
  • 依托单位:
ION CHANNEL DETERMINANTS OF MAST CELL ACTION IN THE HEART
  • 批准号:
    8167745
  • 项目类别:
  • 资助金额:
    $11.72万
  • 财政年份:
    2010
  • 负责人:
    Alexander James Stokes
  • 依托单位:
海外基金